ArticleDevelopment (Cambridge, England)2018
Transfection of
Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- The evolutionary foundations of transcriptional regulation in animals.Nature reviews. Genetics · 2025Review
- Lipids from a snail host regulate the multicellular behavior of a predator of parasitic schistosomes.iScience · 2024Article
- Assembling a Hippo: the evolutionary emergence of an animal developmental signaling pathway.Trends in biochemical sciences · 2024Review
- Article
- Host lipids regulate multicellular behavior of a predator of a human pathogen.bioRxiv : the preprint server for biology · 2024Article
- The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals.bioRxiv : the preprint server for biology · 2024Article
- Pathway to Independence: the future of developmental biology.Development (Cambridge, England) · 2023Article
- Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.Molecular cell · 2023Article
- Transfection of Sponge Cells and Intracellular Localization of Cancer-Related MYC, RRAS2, and DRG1 Proteins.Marine drugs · 2023Article
- Genome editing in the unicellular holozoaneLife · 2022Article
- An evolutionary and physiological perspective on cell-substrate adhesion machinery for cell migration.Frontiers in cell and developmental biology · 2022Review
- Article
- The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition.Open biology · 2021Review
- Temperature sensitivities of metazoan and pre-metazoan Src kinases.Biochemistry and biophysics reports · 2020Article
- Cell cycle transcriptomics of Capsaspora provides insights into the evolution of cyclin-CDK machinery.PLoS genetics · 2020Article
- Transfection of choanoflagellates illuminates their cell biology and the ancestry of animal septins.Molecular biology of the cell · 2018Article
- Patterns of Ancestral Animal Codon Usage Bias Revealed through Holozoan Protists.Molecular biology and evolution · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How animals emerged from their unicellular ancestor remains a major evolutionary question. New genome data from the closest unicellular relatives of animals have provided important insights into the evolution of animal multicellularity. We know that the unicellular ancestor of animals had an unexpectedly complex genetic repertoire, including many genes that are key to animal development and multicellularity. Thus, assessing the function of these genes among unicellular relatives of animals is key to understanding how they were co-opted at the onset of the Metazoa. However, such analyses have been hampered by the lack of genetic tools. Progress has been made in choanoflagellates and teretosporeans, two of the three lineages closely related to animals, whereas no tools are yet available for functional analysis in the third lineage: the filastereans. Importantly, filastereans have a striking repertoire of genes involved in transcriptional regulation and other developmental processes. Here, we describe a reliable transfection method for the filasterean
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.