Evidence map›Paper›PMID 29752343›Full record

ArticleBioscience reports2018

Unexpected role of the human cytomegalovirus contribute to essential hypertension in the Kazakh Chinese population of Xinjiang.

Qian Feng, Jing Hui, Na Tang, Yong-Min Liu, Hua Zhong, Zhen Li, La-Mei Wang, Yuan-Yuan Qu, Feng-Mei Deng, Fang He

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Qian FengDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China.
Jing HuiDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China.
Na TangDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China.
Yong-Min LiuDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China.
Hua ZhongDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China.
Zhen LiDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China.
La-Mei WangCentre of Medical Functional Experiments, Medical College of Shihezi University, Shihezi, China.
Yuan-Yuan QuDepartment of Respiration Medicine, The First Affiliated Hospital of Medical College of Shihezi University, Shihezi, Xijiang, China.
Feng-Mei DengDepartment of Pathophysiology, Chengdu Medical College, Sichuan, China.
Fang HeDepartment of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China fangf2002shz@126.com.
Shihezi University · CNChengdu Medical College · CNFirst Affiliated Hospital of Shihezi University Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) infection, chronic inflammation and oxidative stress, the renin-angiotensin system (RAS), endothelial function, and DNA methylation play roles in the pathogenesis of essential hypertension (EH); however, the mechanism by which HCMV predisposes patients to hypertension remain unclear. Our group previously demonstrated an association between EH and HCMV infection in Kazakh Chinese. Here, we investigated the relationship between HCMV infection and other clinicopathological features in 720 Kazakh individuals with or without hypertension (

Indexed as

8-Hydroxy-2'-DeoxyguanosineAdolescentAdultAgedAged, 80 and overAntibodies, ViralBlood PressureCase-Control StudiesChinaCytomegalovirusCytomegalovirus InfectionsDeoxyguanosineEssential HypertensionEthnicityFemaleHumans3 beta-hydroxysteroid dehydrogenase type II8-Hydroxy-2'-DeoxyguanosineACE protein, humanAntibodies, ViralDeoxyguanosineNitric Oxide Synthase Type IIINOS3 protein, humanPeptidyl-Dipeptidase AProgesterone ReductaseReninTumor Necrosis Factor-alphaEssential hypertensionHuman cytomegalovirusInflammatory responseMethylationOxidative stressRenin-angiotensin system

Identifiers

PMID29752343
PMCPMC6019381
OpenAlexW2800778873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.