Evidence map›Paper›PMID 29752335›Full record

ArticleBioscience reports2018

Retraction of rod-like mitochondria during microtubule-dependent transport.

María Cecilia De Rossi, Valeria Levi, Luciana Bruno

Abstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

María Cecilia De RossiDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IQUIBICEN-CONICET, Ciudad Universitaria, Ciudad de Buenos Aires CP1428, Argentina.
Valeria LeviDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IQUIBICEN-CONICET, Ciudad Universitaria, Ciudad de Buenos Aires CP1428, Argentina vlevi12@gmail.com lbruno@df.uba.ar.
Luciana BrunoDepartamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IFIBA-CONICET, Ciudad Universitaria, Ciudad de Buenos Aires CP1428, Argentina vlevi12@gmail.com lbruno@df.uba.ar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular motors play relevant roles on the regulation of mitochondria size and shape, essential properties for the cell homeostasis. In this work, we tracked single rod-shaped mitochondria with nanometer precision to explore the performance of microtubule motor teams during processive anterograde and retrograde transport. We analyzed simultaneously the organelle size and verified that mitochondria retracted during retrograde transport with their leading tip moving slower in comparison with the rear tip. In contrast, mitochondria preserved their size during anterograde runs indicating a different performance of plus-end directed teams. These results were interpreted considering the different performance of dynein and kinesin teams and provide valuable information on the collective action of motors during mitochondria transport.

Indexed as

AnimalsDyneinsHomeostasisKinesinsMicrotubulesMitochondriaOrganelle ShapeSingle-Cell AnalysisXenopus laevisDyneinsKinesinsintracellular transportmitochondriamolecular motorsXenopus laevis melanophores

Identifiers

PMID29752335
PMCPMC6013701

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.