ArticleThe Journal of pediatrics2018
Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes.
Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Correlation Analysis Between Obesity Index and Glycosylated Hemoglobin Level in Type 2 Diabetes Patients: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Longitudinal evaluation of glomerular filtration rate across adolescence and early adulthood in youth with type 1 diabetes: associations with clinical and social risk factors.Frontiers in endocrinology · 2026Article
- Parent and adolescent perspectives on a novel transdisciplinary model of healthcare delivery for type 1 diabetes.Clinical practice in pediatric psychology · 2024Article
- Exploring Mediators of Mental Health Service Use Among Transgender Individuals in Ontario, Canada.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023Article
- Review
- What can we learn from β-cell failure biomarker application in diabetes in childhood? A systematic review.World journal of diabetes · 2021Article
- Barriers and Facilitators to Involvement in Children's Diabetes Management Among Minority Parents.Journal of pediatric psychology · 2020Article
- The Role of Chemokines and Chemokine Receptors in Diabetic Nephropathy.International journal of molecular sciences · 2020Review
- Deprivation and kidney disease-a predictor of poor outcomes.Clinical kidney journal · 2020Article
- The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange.Diabetes care · 2020Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveTo examine the relationship between the social determinants of health and markers of early renal injury in adolescent patients with type 1 diabetes (T1D). STUDY
designRenal outcomes included estimated glomerular filtration rate (eGFR) and albumin-creatinine excretion ratio (ACR). Differences in urinary and serum inflammatory markers also were assessed in relation to social determinants of health. Regression analysis was used to evaluate the association between the Ontario Marginalization Index (ON-Marg) as a measure of the social determinants of health, patient characteristics, ACR, eGFR, and renal filtration status (hyperfiltration vs normofiltration).
resultsParticipants with T1D (n = 199) with a mean age of 14.4 ± 1.7 years and diabetes duration of 7.2 ± 3.1 years were studied. Mean eGFR was 122.0 ± 19.4 mL/min/1.73 m
conclusionIncreasing marginalization is significantly associated with both eGFR and hyperfiltration in adolescents with T1D and is associated with significant changes in urinary inflammatory biomarkers. These findings highlight a potentially important interaction between social and biological determinants of health in adolescents with T1D.
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