Evidence map›Paper›PMID 29752147›Full record

ArticleTrends in parasitology2018

Sex in Plasmodium falciparum: Silence Play between GDV1 and HP1.

Edward Rea, Karine G Le Roch, Rita Tewari

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Microorganisms · 2022
    Article
  3. Article
  4. Article
  5. The Modular Circuitry of Apicomplexan Cell Division Plasticity.Frontiers in cellular and infection microbiology · 2021
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Edward ReaSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
Karine G Le RochDepartment of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA 92521, USA.
Rita TewariSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK. Electronic address: rita.tewari@nottingham.ac.uk.

Funding

Chromatin structure and control of gene expression in the human malaria parasiteR01AI136511 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI LE ROCH, KARINE GAELLE · 2018 to 2022
$3.4M
The spatial organization of the Plasmodium genome throughout its infectious cycleR01AI106775 · NIAID · UNIVERSITY OF WASHINGTON · PI LE ROCH, KARINE GAELLE, NOBLE, WILLIAM STAFFORD · 2013 to 2016
$1.8M
Biotechnology and Biological Sciences Research Council BB/N017609/1Medical Research Council G0900109Medical Research Council G0900278Medical Research Council MR/K011782/1Medical Research Council MR/N023048/1NIAID NIH HHS R01 AI106775NIAID NIH HHS R01 AI136511
6 · The paper itself

Abstract

Understanding how malaria parasites commit to sexual development is key to the development of transmission-blocking strategies. Recent work by Filarsky and colleagues extends our understanding of the molecular mechanisms driving this process by characterizing an early factor in gametocytogenesis, and showing how this fits neatly into our current knowledge of sexual commitment.

Indexed as

Chromosomal Proteins, Non-HistonePlasmodium falciparumMalaria, FalciparumChromosomal Proteins, Non-Histone

Identifiers

PMID29752147
PMCPMC6122602

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.