Evidence map›Paper›PMID 29751833›Full record

ArticleBMC pediatrics2018

Patterns of early life body mass index and childhood overweight and obesity status at eight years of age.

Joseph M Braun, Heidi J Kalkwarf, George D Papandonatos, Aimin Chen, Bruce P Lanphear

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00129324 (Neurobehavioral Effects of Prevalent Neurotoxicants in Children), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00129324 nacompletednot on this map

Neurobehavioral Effects of Prevalent Neurotoxicants in Children: A Cohort Study of the Cincinnati Center for Children's Environmental Health

TypeinterventionalSponsorNational Institute of Environmental Health Sciences (NIEHS)Ran2003 to 2018Enrolled468ConditionsEnvironmental Exposures, Child Development, Lead and Injury ReductionArmsLead Hazard Control Intervention, Injury Hazard Control Intervention
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Joseph M BraunDepartment of Epidemiology, Brown University, Box G-S121-2, Providence, RI, 02912, USA. joseph_braun_1@brown.edu.ORCID 0000-0002-5239-3235
Heidi J KalkwarfDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
George D PapandonatosDepartment of Biostatistics, Brown University, Providence, RI, 02912, USA.
Aimin ChenDepartment of Environmental Health, University of Cincinnati, Cincinnati, OH, 45267, USA.
Bruce P LanphearChild and Family Research Institute, BC Children's and Women's Hospital, Vancouver, BC, Canada.
Brown University · USChild and Family Research Institute · CACincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
Developmental neurotoxicity of organophosphate and novel brominated flame retardants in childrenR01ES028277 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI CHEN, AIMIN · 2017 to 2022
$3.4M
Early life perfluoroalkyl substance exposure & obesity: Mechanisms & phenotypingR01ES025214 · NIEHS · BROWN UNIVERSITY · PI BRAUN, JOSEPH M · 2016 to 2020
$3.1M
Longitudinal study of exposure to PBDEs and PFCs and child neurobehaviorR01ES020349 · NIEHS · UNIVERSITY OF CINCINNATI · PI CHEN, AIMIN, LANPHEAR, BRUCE P · 2011 to 2015
$2.9M
NIDDK NIH HHS P30 DK078392NIEHS NIH HHS R01 ES020349NIEHS NIH HHS R01 ES025214NIEHS NIH HHS R01 ES028277
6 · The paper itself

Abstract

backgroundExcess weight gain in infancy and childhood is associated with increased risk of subsequent obesity. Identifying patterns of infancy and childhood weight gain associated with subsequent obesity or overweight status could help identify children at highest risk. Thus, we examined patterns of infancy and early childhood BMI in relation to mid-childhood overweight and obesity status.

methodsIn a prospective cohort of 215 children from Cincinnati, OH (born: 2003-2006), we measured weight and length or height at ages 4 weeks and 1, 2, 3, 4, 5, and 8 years. We calculated BMI z-scores using World Health Organization references. Using linear fixed effect models, we estimated mean BMI at each age and rates of change in BMI between ages 4 weeks and 5 years by children's overweight and obesity status at age 8 years, assessed with BMI z-scores or bioelectric impedance analysis (BIA).

resultsChildren who became overweight (BMI, n = 51 and BIA, n = 37) or obese (BMI, n = 22 and BIA, n = 29) at age 8 years had greater BMI at all ages compared to normal weightchildren. Children who were overweight had similar rates of change in BMI as children who were lean. Children who were obese had greater gains in BMI between age 4 weeks and 5 years, with the most rapid gains in the first 2 years.

conclusionsResults from this study of modest sample size, suggest that adiposity patterns in the first 5 years of life are related to subsequent childhood overweight and obesity risk.

Indexed as

Body Mass IndexAdiposityBody HeightBody WeightChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleOhioOverweightPediatric ObesityProspective StudiesRisk FactorsAdiposityAnd rapid growthChildrenEpidemiologyObesity

Identifiers

PMID29751833
PMCPMC5948906
OpenAlexW2799332143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.