Evidence map›Paper›PMID 29751793›Full record

ArticleBMC cancer2018

Uptake of three doses of HPV vaccine by primary school girls in Eldoret, Kenya; a prospective cohort study in a malaria endemic setting.

Hillary Mabeya, Sonia Menon, Steven Weyers, Violet Naanyu, Emily Mwaliko, Elijah Kirop, Omenge Orango, Heleen Vermandere, Davy Vanden Broeck

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  13. Mapping Evidence on Management of Cervical Cancer in Sub-Saharan Africa: Scoping Review.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Hillary MabeyaMoi University, Eldoret, Kenya. mabeya4@gmail.com.
Sonia MenonInternational Center of Reproductive Health, Ghent University, De Pintelaan 185 P3, 9000, Ghent, Belgium.
Steven WeyersGhent University, Ghent, Belgium.
Violet NaanyuMoi University, Eldoret, Kenya.
Emily MwalikoMoi University, Eldoret, Kenya.
Elijah KiropMoi University, Eldoret, Kenya.
Omenge OrangoMoi University, Eldoret, Kenya.
Heleen VermandereInternational Center of Reproductive Health, Ghent University, De Pintelaan 185 P3, 9000, Ghent, Belgium.
Davy Vanden BroeckInternational Center of Reproductive Health, Ghent University, De Pintelaan 185 P3, 9000, Ghent, Belgium.
Moi University · KEGhent University Hospital · BECDC Foundation · US

Funding

Merck 3000546647
6 · The paper itself

Abstract

backgroundAll women are potentially at risk of developing cervical cancer at some point in their life, yet it is avoidable cause of death among women in Sub- Saharan Africa with a world incidence of 530,000 every year. It is the 4th commonest cancer affecting women worldwide with over 260,000 deaths reported in 2012. Low resource settings account for over 75% of the global cervical cancer burden. Uptake of HPV vaccination is limited in the developing world. WHO recommended that 2 doses of HPV vaccine could be given to young girls, based on studies in developed countries. However in Africa high rates of infections like malaria and worms can affect immune responses to vaccines, therefore three doses may still be necessary. The aim of this study was to identify barriers and facilitators associated with uptake of HPV vaccine.

methodsA cross-sectional survey was conducted at Eldoret, Kenya involving 3000 girls aged 9 to 14 years from 40 schools. Parents/guardians gave consent through a questionnaire.

resultsOf all 3083 the school girls 93.8% had received childhood vaccines and 63.8% had a second HPV dose, and 39.1% had a third dose. Administration of second dose and HPV knowledge were both strong predictors of completion of the third dose. Distance to the hospital was a statistically significant risk factor for non-completion (P: 0.01).

conclusionsDistance to vaccination centers requires a more innovative vaccine-delivery strategy and education of parents/guardians on cervical screening to increase attainment of the HPV vaccination.

Indexed as

AdolescentChildCross-Sectional StudiesEndemic DiseasesFemaleHealth Knowledge, Attitudes, PracticeHumansImmunization ScheduleImmunogenicity, VaccineIncidenceKenyaMalariaPapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CareProspective StudiesPapillomavirus VaccinesDeterminantsGardasilHPV vaccinationKenyaMalariaParents/guardians

Identifiers

PMID29751793
PMCPMC5948818
OpenAlexW2800668505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.