Evidence map›Paper›PMID 29751629›Full record

ReviewNutrients2018

Current Evidence about Nutrition Support in Cardiac Surgery Patients-What Do We Know?

Aileen Hill, Ekaterina Nesterova, Vladimir Lomivorotov, Sergey Efremov, Andreas Goetzenich, Carina Benstoem, Mikhail Zamyatin, Michael Chourdakis, Daren Heyland, Christian Stoppe

Registry-linked trialAbstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06146426 (Effects of Early Oral Diet After Cardiac Surgery), which is not on this map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06146426 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Early Oral Diet After Cardiac Surgery: an Open Label Randomized Controlled Trial

TypeinterventionalSponsorHamad Medical CorporationRan2023 to 2025Enrolled196ConditionsAdult Cardiac SurgeryArmsEarly diet resumption
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Observational
  8. Article
  9. Article
  10. Comparison between the NUTRIC score and modified NUTRIC score to predict hospital mortality in patients undergoing cardiac surgery: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article
  11. Fast-Track Extubation After Cardiac Surgery: A Narrative Review.Journal of cardiovascular development and disease · 2025
    Review
  12. Article
  13. Observational
  14. Adequacy of oral intakes after cardiac surgery within an ERAS pathway: A prospective observational study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Observational
  15. Observational
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aileen HillDepartment of Intensive Care Medicine, University Hospital RWTH, D-52074 Aachen, Germany. ahill@ukaachen.de.ORCID 0000-0002-7013-3357
Ekaterina NesterovaDepartment of Anesthesiology and Intensive Care Medicine, National Pirogov Medical Center, 105203 Moscow, Russia. d10001letopisec@mail.ru.
Vladimir LomivorotovDepartment of Anesthesiology and Intensive Care Medicine, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. v.lomivorotov@gmail.com.
Sergey EfremovDepartment of Anesthesiology and Intensive Care Medicine, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. sergefremov@mail.ru.ORCID 0000-0001-5581-9169
Andreas Goetzenich3CARE-Cardiovascular Critical Care & Anesthesia Evaluation and Research, D-52074 Aachen, Germany. andreas@goetzenich.net.
Carina BenstoemDepartment of Intensive Care Medicine, University Hospital RWTH, D-52074 Aachen, Germany. cbenstoem@ukaachen.de.
Mikhail ZamyatinDepartment of Anesthesiology and Intensive Care Medicine, National Pirogov Medical Center, 105203 Moscow, Russia. zamyatinmn@pirogov-center.ru.ORCID 0000-0002-2072-7798
Michael ChourdakisDepartment of Medicine, School of Health Sciences, 54124 Thessaloniki, Greece. mhourd@gapps.auth.gr.ORCID 0000-0002-9490-8356
Daren HeylandClinical Evaluation Research Unit, Kingston General Hospital, Kingston, ON K7L 2V7, Canada. dkh2@queensu.ca.
Christian StoppeDepartment of Intensive Care Medicine, University Hospital RWTH, D-52074 Aachen, Germany. christian.stoppe@gmail.com.ORCID 0000-0002-2028-2039

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrition support is increasingly recognized as a clinically relevant aspect of the intensive care treatment of cardiac surgery patients. However, evidence from adequate large-scale studies evaluating its clinical significance for patients’ mid- to long-term outcome remains sparse. Considering nutrition support as a key component in the perioperative treatment of these critically ill patients led us to review and discuss our understanding of the metabolic response to the inflammatory burst induced by cardiac surgery. In addition, we discuss how to identify patients who may benefit from nutrition therapy, when to start nutritional interventions, present evidence about the use of enteral and parenteral nutrition and the potential role of pharmaconutrition in cardiac surgery patients. Although the clinical setting of cardiac surgery provides advantages due to its scheduled insult and predictable inflammatory response, researchers and clinicians face lack of evidence and several limitations in the clinical routine, which are critically considered and discussed in this paper.

Indexed as

Nutritional SupportPostoperative CareCardiovascular DiseasesCritical CareCritical IllnessHumansInflammationMicronutrientsNon-Randomized Controlled Trials as TopicNutritional RequirementsNutritional StatusObservational Studies as TopicPerioperative CareRandomized Controlled Trials as TopicMicronutrientscardiac surgerycardiopulmonary bypassenteral nutritionnutrition risk stratificationpharmaconutritionpostoperative nutritional managementsupplemental parenteral nutritionsystemic inflammatory responseunderfeeding

Identifiers

PMID29751629
PMCPMC5986477

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.