Evidence map›Paper›PMID 29751524›Full record

ArticleMolecules (Basel, Switzerland)2018

β-Asarone Induces Apoptosis and Cell Cycle Arrest of Human Glioma U251 Cells via Suppression of HnRNP A2/B1-Mediated Pathway In Vitro and In Vivo.

Li Li, Yi Yang, Mingxia Wu, Zanyang Yu, Chengqiang Wang, Guojun Dou, Hui He, Hongmei Wang, Na Yang, Hongyi Qi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. PTBP1 and Cancer: From RNA Regulation to Therapeutic Potential.Journal of cellular and molecular medicine · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Ethnic, Botanic, Phytochemistry and Pharmacology of theMolecules (Basel, Switzerland) · 2023
    Review
  7. Review
  8. The Critical Role of RNA mCellular and molecular neurobiology · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. The HNRNPA2B1-MST1R-Akt axis contributes to epithelial-to-mesenchymal transition in head and neck cancer.Laboratory investigation; a journal of technical methods and pathology · 2020
    Article
  14. β-Asarone Exerts Antioxidative Effects on HNeurochemical research · 2020
    Article
  15. Article
  16. RNA-binding proteins in tumor progression.Journal of hematology & oncology · 2020
    Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Li LiCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. lilyli@email.swu.edu.cn.
Yi YangCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. doria11@email.swu.edu.cn.
Mingxia WuCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. zhangww_2005@126.com.
Zanyang YuCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. y1128y@email.swu.edu.cn.
Chengqiang WangCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. wangchengqiang432@163.com.
Guojun DouCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. guojundou@163.com.
Hui HeCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. hehui662299@163.com.
Hongmei WangCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. wanglitcm@sina.com.
Na YangInstitute of Laboratory Animal Sciences, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610212, China. nanayang@yeah.net.
Hongyi QiCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. hongyiqi@swu.edu.cn.ORCID 0000-0003-0564-3892
Xiaoyu XuCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. xuxiaoyu@swu.edu.cn.
Southwest University · CNSichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HnRNP A2/B1 has been found to be an oncogenic protein strongly related to the growth of human glioma cells. Herein, β-asarone, the main component in the volatile oil of

Indexed as

Allylbenzene DerivativesAnimalsAnisolesApoptosisBrain NeoplasmsCell Cycle CheckpointsCell Line, TumorCell ProliferationCell SurvivalDisease Models, AnimalGliomaHeterogeneous-Nuclear Ribonucleoprotein Group A-BHumansMiceMitochondriaProto-Oncogene Proteins c-bcl-2Allylbenzene DerivativesAnisolesasaroneHeterogeneous-Nuclear Ribonucleoprotein Group A-BhnRNP A2Proto-Oncogene Proteins c-bcl-2alternative splicingapoptosiscell cycle arrestgliomahnRNPA2/B1β-asarone

Identifiers

PMID29751524
PMCPMC6100535
OpenAlexW2800451912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.