Evidence map›Paper›PMID 29751134›Full record

ArticleJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2018

Sarcopenia in Resected NSCLC: Effect on Postoperative Outcomes.

Ryota Nakamura, Yoshihisa Inage, Rika Tobita, Satoshi Yoneyama, Takeshi Numata, Kyoko Ota, Hidetoshi Yanai, Takeo Endo, Yukinori Inadome, Shingo Sakashita and 3 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 2 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 2 syntheses or guidelines pooled it, 149 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Effect of preoperative cancer cachexia on postoperative sarcopenia in patients with non-small cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  19. Article
  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Ryota NakamuraDepartment of Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan. Electronic address: ryo-naka@mail.goo.ne.jp.
Yoshihisa InageDepartment of Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan.
Rika TobitaDepartment of Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan.
Satoshi YoneyamaDepartment of Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan.
Takeshi NumataDepartment of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Kyoko OtaDepartment of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Hidetoshi YanaiDepartment of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Takeo EndoDepartment of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Yukinori InadomeDepartment of Pathology, Institute of Clinical Medicine, University of Tsukuba. Tsukuba, Ibaraki, Japan.
Shingo SakashitaDepartment of Pathology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Hiroaki SatohDivision of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Kenji YuzawaDepartment of Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan.
Toru TerashimaDepartment of Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan.
University of Tsukuba · JPNational Hospital Organization Mito Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSkeletal muscle depletion, referred to as sarcopenia, has recently been identified as a risk factor for poor outcomes in various malignancies. However, the prognostic significance of sarcopenia in patients with NSCLC after surgery has not been adequately determined. This study investigated the impact of sarcopenia in patients undergoing pulmonary resection for lung cancer.

methodsThis retrospective study consisted of 328 patients with pathologically confirmed NSCLC who underwent curative resection between January 2005 and April 2017. Preoperative computed tomography imaging at the third lumbar vertebrae level was assessed to measure the psoas muscle mass index (PMI, cm

resultsThe median patient age was 71 years and 59% were male. Sarcopenia was present in 183 (55.8%) and was significantly related with increasing age (p < 0.001), being male (p < 0.001), smoking habit (p < 0.001), lower body mass index (p < 0.001), and postoperative major complication (Clavien-Dindo grade ≥3, p = 0.036). The prevalence of sarcopenia was higher in men than in women, and the prevalence increased with age in men, whereas the prevalence did not increase in females older than 70 years. The 5-year survival rate was 61% in patients with sarcopenia and 91% in those without. Multivariate analysis revealed that sarcopenia was an independent unfavorable prognostic factor (p = 0.019).

conclusionsSarcopenia as determined using preoperative computed tomography could be used to predict postoperative major complication and prognosis in patients with resected NSCLC. Our results may provide some important information for preoperative management.

Indexed as

Postoperative ComplicationsAdenocarcinomaAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedPneumonectomyPrognosisRetrospective StudiesSarcopeniaNSCLCPsoas muscle indexSarcopeniaSurgery

Identifiers

PMID29751134
OpenAlexW2799808995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.