ArticleThe journal of physical chemistry letters2018
In Situ Identification of Nanoparticle Structural Information Using Optical Microscopy.
Article in The journal of physical chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Heterogeneous Reactivity of Palladium Nanoparticles Revealed by Wavelength-Resolved Interferometric Scattering.Nano letters · 2026Article
- High-Curvature Features Improve Targeting of Nanoconstructs with Small-Molecule Ligands.Nano letters · 2026Article
- Learning from Metal Nanocrystal Heterogeneity: A Need for Information-Rich and High-Throughput Single-Nanocrystal Measurements.ACS nanoscience Au · 2025Review
- Article
- Ligand Separation on Nanoconstructs Affects Targeting Selectivity to Protein Dimers on Cell Membranes.Nano letters · 2024Article
- Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles.International journal of nanomedicine · 2022Review
- Nanoparticle Shape Determines Dynamics of Targeting Nanoconstructs on Cell Membranes.Journal of the American Chemical Society · 2021Article
- Single-Nanoparticle Orientation Sensing by Deep Learning.ACS central science · 2020Article
- Resolving Single-Nanoconstruct Dynamics during Targeting and Nontargeting Live-Cell Membrane Interactions.ACS nano · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Diffraction-limited optical microscopy lacks the resolution to directly characterize nanoscale features of single nanoparticles. This paper describes how structural features of gold nanostars can be identified using differential interference contrast (DIC) microscopy. First, we established structure-property relationships between categories of nanoparticle shapes and DIC optical images and then validated the correlation with electrodynamic simulations and electron microscopy. We found that DIC image patterns of single nanostars could be differentiated between 2D and 3D geometries. DIC images were also used to distinguish asymmetric and 4-fold symmetric structures and track nanoparticle orientation. Finally, we demonstrated how this wide-field optical technique can be used for in situ characterization of single nanoparticles rotating at a glass-water interface.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.