Evidence map›Paper›PMID 29750156›Full record

ReviewBioMed research international2018

Right Ventricle Remodeling and Function in Scleroderma Patients.

Roxana Cucuruzac, Iolanda Muntean, Imre Benedek, Andras Mester, Nora Rat, Adriana Mitre, Monica Chitu, Theodora Benedek

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Roxana CucuruzacUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Iolanda MunteanUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.ORCID 0000-0002-9930-018X
Imre BenedekUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Andras MesterUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Nora RatUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Adriana MitreUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Monica ChituUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Theodora BenedekUniversity of Medicine and Pharmacy of Târgu Mureș, Gh. Marinescu Street, No. 38, 540139 Tîrgu Mureș, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scleroderma, known also as systemic sclerosis (SSc), is a severe disease associated with high mortality rates, and right ventricular (RV) remodeling and dysfunction, along with pulmonary artery hypertension (PAH), are among the most important internal organ manifestations of this disease. PAH has a higher prevalence in patients with SSc compared to the general population and represents a significant predictor of mortality in SSc. In patients with SSc, the morphological remodeling and alteration of RV function begin even before the setting of PAH and lead to development of a specific adaptive pattern of the RV which is different from the one recorded in patients with IAPH. These alterations cause worse outcomes and increased mortality rates in SSc patients. Early detection of RV dysfunction and remodeling is possible using modern imaging tools currently available and can indicate the initiation of specific therapeutic measures before installation of PAH. The aim of this review is to summarize the current knowledge related to mechanisms involved in the remodeling and functional alteration of the RV in SSc patients.

Indexed as

HumansHypertension, PulmonaryScleroderma, SystemicVentricular Dysfunction, RightVentricular Function, RightVentricular Remodeling

Identifiers

PMID29750156
PMCPMC5884238
OpenAlexW2790830170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.