Evidence map›Paper›PMID 29749614›Full record

ArticleImmunology2018

MicroRNA signature of central nervous system-infiltrating dendritic cells in an animal model of multiple sclerosis.

Mariah L Hoye, Angela S Archambault, Taylor M Gordon, Landon K Oetjen, Matthew D Cain, Robyn S Klein, Seth D Crosby, Brian S Kim, Timothy M Miller, Gregory F Wu

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Paradoxical Expression of Ionotropic Glutamate Receptors in Leucocytes.Clinical reviews in allergy & immunology · 2026
    Article
  2. Frontiers in cellular neuroscience · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Environmental Influencers, MicroRNA, and Multiple Sclerosis.Journal of central nervous system disease · 2020
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mariah L HoyeDepartment of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Angela S ArchambaultDepartment of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Taylor M GordonDepartment of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Landon K OetjenDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Matthew D CainDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Robyn S KleinDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Seth D CrosbyGenome Technology Access Center, Washington University School of Medicine, St Louis, MO, USA.
Brian S KimDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Timothy M MillerDepartment of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Gregory F WuDepartment of Neurology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0003-3588-0637
Washington University in St. Louis · US

Funding

Using motor neuron specific miRNA to understand and develop novel therapeutics for motor neuron diseaseR01NS078398 · NINDS · WASHINGTON UNIVERSITY · PI MILLER, TIMOTHY M. · 2012 to 2021
$3.9M
ROLE OF B CELL ANTIGEN PRESENTATION IN AUTOIMMUNE ENCEPHALOMYELITISR01NS083678 · NINDS · WASHINGTON UNIVERSITY · PI WU, GREGORY · 2013 to 2017
$1.7M
Defining Motor Neuron-Specific miRNAs in ALSF31NS092340 · NINDS · WASHINGTON UNIVERSITY · PI HOYE, MARIAH LAWLER · 2015 to 2017
$90k
NINDS NIH HHS F31 NS092340NINDS NIH HHS F31NS092340NINDS NIH HHS R01 NS078398NINDS NIH HHS R01NS078398NINDS NIH HHS R01 NS083678NINDS NIH HHS R01NS083678
6 · The paper itself

Abstract

Innate immune cells are integral to the pathogenesis of several diseases of the central nervous system (CNS), including multiple sclerosis (MS). Dendritic cells (DCs) are potent CD11c

Indexed as

AnimalsCentral Nervous SystemDendritic CellsDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalInflammationMiceMice, Inbred C57BLMicroRNAsMultiple SclerosisMicroRNAsdendritic cellsmicroRNAsmultiple sclerosisneuroinflammation

Identifiers

PMID29749614
PMCPMC6099169
OpenAlexW2799431856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.