Evidence map›Paper›PMID 29749398›Full record

ArticleLeukemia2018

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.

Elaine G Garcia, Sowmya Iyer, Sara P Garcia, Siebe Loontiens, Ruslan I Sadreyev, Frank Speleman, David M Langenau

Open access · bronzeAbstract read
In one paragraph

Article in Leukemia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Zebrafish models of acute leukemias: Current models and future directions.Wiley interdisciplinary reviews. Developmental biology · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Tackling Acute Lymphoblastic Leukemia-One Fish at a Time.International journal of molecular sciences · 2019
    Review
  15. Modeling hematopoietic disorders in zebrafish.Disease models & mechanisms · 2019
    Review
  16. Article
  17. Zebrafish MYC-induced leukemia models: uniqueInternational journal of hematologic oncology · 2019
    Article
  18. Genetic Models of Leukemia in Zebrafish.Frontiers in cell and developmental biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Elaine G GarciaDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.
Sowmya IyerDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.
Sara P GarciaDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.ORCID http://orcid.org/0000-0003-3312-6454
Siebe LoontiensCancer Research Institute Ghent (CRIG) and Center for Medical Genetics, Ghent University, Ghent, Belgium.
Ruslan I SadreyevDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.
Frank SpelemanCancer Research Institute Ghent (CRIG) and Center for Medical Genetics, Ghent University, Ghent, Belgium.
David M LangenauDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA. dlangenau@mgh.harvard.edu.
Massachusetts General Hospital · USGhent University · BE

Funding

Immune Compromises Zebrafish for Cell TransplantationR24OD016761 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI LANGENAU, DAVID MICHAEL · 2013 to 2021
$5.2M
Oncogenic pathways and therapeutic targets in T cell acute lymphoblastic leukemiaR01CA211734 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LANGENAU, DAVID MICHAEL · 2017 to 2021
$1.9M
NCI NIH HHS R01 CA211734NIH HHS R24 OD016761
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell LineageAnimalsAnimals, Genetically ModifiedB-LymphocytesClone CellsHumansNeoplastic Stem CellsPrecursor Cell Lymphoblastic Leukemia-LymphomaT-LymphocytesTumor Cells, CulturedZebrafish

Identifiers

PMID29749398
PMCPMC6620784
OpenAlexW2803013290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.