Evidence map›Paper›PMID 29749364›Full record

ArticleThe Indian journal of medical research2018

Cytopenia in adult brucellosis patients.

Safak Kaya, Nazif Elaldi, Ozcan Deveci, Ahmet Emre Eskazan, Muhammed Bekcibasi, Salih Hosoglu

Open access · diamondAbstract read
In one paragraph

Article in The Indian journal of medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Brucellosis complicated by myelofibrosis: report of five cases and review of literature.International journal of clinical and experimental pathology · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. A Case of Brucellosis with Possible Ileal Involvement.GE Portuguese journal of gastroenterology · 2020
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Safak KayaDepartment of Infectious Diseases & Clinical Microbiology, Gazi Yasargil Training & Research Hospital, Diyarbakir, Turkey.
Nazif ElaldiDepartment of Infectious Diseases & Clinical Microbiology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey.
Ozcan DeveciDepartment of Infectious Diseases & Clinical Microbiology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Ahmet Emre EskazanDepartment of Internal Medicine, Division of Hematology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Muhammed BekcibasiDepartment of Infectious Diseases & Clinical Microbiology, Bismil State Hospital, Diyarbakir, Turkey.
Salih HosogluDepartment of Infectious Diseases & Clinical Microbiology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Dicle University · TRDiyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi · TRIstanbul University-Cerrahpaşa · TRSivas Cumhuriyet Üniversitesi · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

objectivesBrucellosis can lead to haematological abnormalities including cytopenia confusing with haematological malignancies. The aim of this study was to compare the main characteristics of brucellosis patients without cytopenia (Group 1) and with cytopenia (Group 2).

methodsThis five-year period study which was performed in two referral hospitals in Turkey, included all adult brucellosis patients. Abnormally, low counts of leucocyte or haemoglobin or platelets in a patient were considered as cytopenia. The demographics, clinical, laboratory, treatment and outcome data were analyzed.

resultsA total of 484 brucellosis patients were enrolled. Among the cases, 162 (33.5%) of them had cytopenia. One hundred and four (21.5%) had anaemia, 88 (18.8%) had thrombocytopenia, 71 (14.6%) had leucopenia and 28 (5.8%) had pancytopenia. The mean age of group 2 was 35.01±16.05 yr and it was 33.31±14.39 yr in group 1. While there was no difference between the groups in terms of duration of treatment, the median length of hospital stay (LOS) was significantly longer in group 2 (9 vs 10 days; P<0.001). The most frequently applied combination therapy consisted of doxycycline plus rifampicin and doxycycline plus streptomycin regimens. No significant difference was observed in terms of duration of treatment, LOS and restoration time of cytopenia between the patients who received either of these combinations. INTERPRETATION &

conclusionsOur findings suggested that the patients with cytopenia should be investigated for brucellosis, especially if living in, or with a history of travel to, endemic areas, in view of the increase in world travel.

Indexed as

AdultAnemiaBrucellosisDoxycyclineFemaleHematologic NeoplasmsHumansMaleMiddle AgedPancytopeniaRifampinStreptomycinThrombocytopeniaTurkeyDoxycyclineRifampinStreptomycinAnaemiabrucellosisleucopeniapancytopeniathrombocytopenia

Identifiers

PMID29749364
PMCPMC5967221
OpenAlexW2801596259

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.