Evidence map›Paper›PMID 29749320›Full record

Trial reportThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2018

Combined treatment for gastric cancer: Immunological approach.

Olzhas Zhandossov, Galina Kaussova, Avraam Koten

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Dealing with the gray zones in the management of gastric cancer: The consensus statement of the İstanbul Group.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Olzhas ZhandossovDepartment of Oncology, Kazakhstan Medical University High School of Public Health, Almaty, Kazakhstan.
Galina KaussovaDepartment of Public Health and Social Sciences, Kazakhstan Medical University High School of Public Health, Almaty, Kazakhstan.
Avraam KotenDepartment of Oncology, Medical Center "CarmelMC", Haifa, Israel.
Kazakhstan Medical University · KZCarmel Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsGastric cancer is one of the most common oncological diseases. It can develop in any part of the stomach and spread to other organs, especially the esophagus, lungs, and liver. The aim of our study was to investigate the effectiveness of our proposed therapy. MATERIALS AND

methodsOur research promises more effective neoadjuvant therapy, including immunotherapy and multi-agent chemotherapy. Of the 62 patients involved in our study, 32 underwent neoadjuvant chemotherapy in combination with surgery, whereas the rest underwent neoadjuvant chemoimmunotherapy with surgery.

resultsInvestigation of T-cell-mediated and humoral immunity in patients with gastric cancer over the course of treatment found a reduction of the main indices of cell-mediated and humoral immunity in the patients who underwent standard therapy, which greatly caused a decline of antitumor, anti-infective, and antitoxic protection of the patients' organisms.

conclusionThis study can contribute to the development of new therapies for gastric cancer as well as other types of cancer.

Indexed as

AgedAntineoplastic AgentsAntineoplastic ProtocolsChemotherapy, AdjuvantCombined Modality TherapyFemaleGastrectomyHumansImmunotherapyMaleMiddle AgedNeoadjuvant TherapyStomach NeoplasmsTreatment OutcomeAntineoplastic Agents

Identifiers

PMID29749320
PMCPMC6284695
OpenAlexW2791253203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.