ArticleClinical cardiology2018
Understanding Patient Adherence and Concerns with STatins and MedicatION Discussions With Physicians (ACTION): A survey on the patient perspective of dialogue with healthcare providers regarding statin therapy.
Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Barriers and facilitators to deprescribing of cardiovascular medications: a systematic review.BMJ open · 2022Pooled it
- Prevalence of statin intolerance: a meta-analysis.European heart journal · 2022 · on this mapPooled it
- Statin treatment after acute coronary syndrome: Adherence and reasons for non-adherence in a randomized controlled intervention trial.Scientific reports · 2019Trial
- The Statin Paradox: Drivers and Consequences of Therapy Discontinuation.Metabolites · 2026Review
- Large Language Model-Based Analysis of Statin Therapy Discussions and Sentiment on Social Media: Cross-Sectional Observational Study.Journal of medical Internet research · 2026Observational
- Addressing adherence challenges in long-term statin treatment among Asian populations: Current gaps and proposed solutions.American journal of preventive cardiology · 2025Review
- The prevalence of gastric reflux symptoms in Saudi Arabian statin-users, and associated factors: a tertiary-center cross-sectional observational study.Annals of medicine and surgery (2012) · 2025Article
- Pharmacogenomic insights into atorvastatin and rosuvastatin adverse effects: a prospective observational study in the UAE's multiethnic population.Human genomics · 2025Observational
- A Systematic Review Uncovering Modifiable Influences on Statin Adherence.Patient preference and adherence · 2025Review
- Lipid-lowering agent preferences among patients with hypercholesterolemia: a focus group study.Journal of pharmaceutical policy and practice · 2024Article
- Optimising adherence to secondary prevention medications following acute coronary syndrome utilising telehealth cardiology pharmacist clinics: a matched cohort study.International journal of clinical pharmacy · 2023Article
- Monitoring Cardiovascular Problems in Heart Patients Using Machine Learning.Journal of healthcare engineering · 2023Article
- Relationships between beliefs about statins and non-adherence in inpatients from Northwestern China: a cross-sectional survey.Frontiers in pharmacology · 2023Article
- Barriers to Follow Up Care in the South Asian Immigrant Population at High Risk of Acute Coronary Syndrome at Elmhurst Hospital Center.Journal of immigrant and minority health · 2022Article
- Patient-Reported Reasons for Switching or Discontinuing Statin Therapy: A Mixed Methods Study Using Social Media.Drug safety · 2022Article
- A Cohort Analysis of Statin Treatment Patterns Among Small-Sized Primary Care Practices.Journal of general internal medicine · 2022Article
- Article
- Ambulatory Heart Function and Transplant Patients' Perceptions of Drug-Drug Interactions: A Qualitative Study.The Canadian journal of hospital pharmacy · 2022Article
- Patient views of therapeutic interchange of ACE inhibitors in Australian primary care: a qualitative study.BMJ open · 2021Article
- Reported muscle symptoms during statin treatment amongst Italian dyslipidaemic patients in the real-life setting: the PROSISA Study.Journal of internal medicine · 2021Observational
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStatins are first-line for cholesterol lowering and prevention of atherosclerotic cardiovascular disease (ASCVD), but their use is complicated by side effects and potential for drug-drug interactions. Provider-patient communication is the basis of the recommended shared decision-making, but relatively little is known about this in the context of statin use.
methodsWe surveyed 5014 US adults prescribed a statin for hypercholesterolemia to learn their perspectives on communication with their provider.
resultsNinety-four percent reported currently taking a statin while 6% had stopped. Past users vs current users were more likely to be female, age < 65 years, and to have fewer cardiovascular disease-related comorbidities (hypertension, type 2 diabetes mellitus, and coronary heart disease, respectively). Although 93% of current statin users were taking ≥1 other prescription medications (median of 4), 76% were "not at all"/"not very concerned" about potential drug-drug interactions with their statin, and fewer than one-quarter recalled mention of these from their provider. Ninety-five percent of subjects said it was "extremely"/"somewhat" important that their healthcare provider take "an individualized approach to selecting the right statin," but 73% and 76%, respectively, said their statin choice was made with little or no input from them. Only 25% were told that "some statins might be more likely than others to interact with other medications," and only 18% (and only 20% of past users) were told that "their particular statin might interact with other medications."
conclusionProvider-patient communication regarding statin therapy appears inadequate, by patient recall, and efforts to improve it are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.