Evidence map›Paper›PMID 29748774›Full record

ArticleChemistry Central journal2018

Structural determinants influencing halogen bonding: a case study on azinesulfonamide analogs of aripiprazole as 5-HT

Krzysztof Marciniec, Rafał Kurczab, Maria Książek, Ewa Bębenek, Elwira Chrobak, Grzegorz Satała, Andrzej J Bojarski, Joachim Kusz, Paweł Zajdel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry Central journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Multi-Target Approach for Drug Discovery against Schizophrenia.International journal of molecular sciences · 2018
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Krzysztof MarciniecDepartment of Organic Chemistry, Medical University of Silesia, 4 Jagiellońska Street, 41-200, Sosnowiec, Poland. kmarciniec@sum.edu.pl.ORCID http://orcid.org/0000-0003-4631-2360
Rafał KurczabDepartment of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343, Krakow, Poland.
Maria KsiążekInstitute of Physics, University of Silesia, 4 Uniwersytecka Street, 40-007, Katowice, Poland.
Ewa BębenekDepartment of Organic Chemistry, Medical University of Silesia, 4 Jagiellońska Street, 41-200, Sosnowiec, Poland.
Elwira ChrobakDepartment of Organic Chemistry, Medical University of Silesia, 4 Jagiellońska Street, 41-200, Sosnowiec, Poland.
Grzegorz SatałaDepartment of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343, Krakow, Poland.
Andrzej J BojarskiDepartment of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343, Krakow, Poland.
Joachim KuszInstitute of Physics, University of Silesia, 4 Uniwersytecka Street, 40-007, Katowice, Poland.
Paweł ZajdelDepartment of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Krakow, Poland.
Maj Institute of Pharmacology · PLInstitute of Physics · PLJagiellonian University · PLMedical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of azinesulfonamide derivatives of long-chain arylpiperazines with variable-length alkylene spacers between sulfonamide and 4-arylpiperazine moiety is designed, synthesized, and biologically evaluated. In vitro methods are used to determine their affinity for serotonin 5-HT

Indexed as

AripiprazoleAzinesulfonamidesCrystal structureHalogen bondLong-chain arylpiperazine

Identifiers

PMID29748774
PMCPMC5945563
OpenAlexW2800343752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.