Evidence map›Paper›PMID 29748655›Full record

ReviewEuropean journal of clinical nutrition2018

Normalizing resting energy expenditure across the life course in humans: challenges and hopes.

Manfred J Müller, Corinna Geisler, Mark Hübers, Maryam Pourhassan, Wiebke Braun, Anja Bosy-Westphal

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Trial
  3. International Society of Sports Nutrition position stand: diets for body weight reduction.Journal of the International Society of Sports Nutrition · 2026
    Review
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  9. Has the BMI had its day?International journal of obesity (2005) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Age But Not Menopausal Status Is Linked to Lower Resting Energy Expenditure.The Journal of clinical endocrinology and metabolism · 2023
    Article
  14. Being a scientist.European journal of clinical nutrition · 2023
    Review
  15. Article
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  17. Article
  18. What Is aNutrients · 2022
    Review
  19. Phenotypic differences between people varying in muscularity.Journal of cachexia, sarcopenia and muscle · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manfred J MüllerInstitute for Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany. mmueller@nutrfoodsc.uni-kiel.de.
Corinna GeislerInstitute for Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany.
Mark HübersInstitute for Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany.
Maryam PourhassanInstitute for Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany.
Wiebke BraunInstitute for Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany.
Anja Bosy-WestphalInstitute for Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whole-body daily energy expenditure is primarily due to resting energy expenditure (REE). Since there is a high inter-individual variance in REE, a quantitative and predictive framework is needed to normalize the data. Complementing the assessment of REE with data normalization makes individuals of different sizes, age, and sex comparable. REE is closely correlated with body mass suggesting its near constancy for a given mass and, thus, a linearity of this association. Since body mass and its metabolic active components are the major determinants of REE, they have been implemented into allometric modeling to normalize REE for quantitative differences in body weight and/or body composition. Up to now, various size and allometric scale laws are used to adjust REE for body mass. In addition, the impact of the anatomical and physical properties of individual body components on REE has been quantified in large populations and for different age groups. More than 80% of the inter-individual variance in REE is explained by FFM and its composition. There is evidence that the impact of individual organs on REE varies between age groups with a higher contribution of brain and visceral organs in children/adolescents compared with adults where skeletal muscle mass contribution is greater than in children/adolescents. However, explaining REE variations by FFM and its composition has its own limitations (inter-correlations of organs/tissues). In future, this could be overcome by re-describing the organ-to-organ variation using principal components analysis and then using the scores on the components as predictors in a multiple regression analysis.

Indexed as

Basal MetabolismEnergy MetabolismBody CompositionBody Mass IndexBody WeightBrainHormonesHumansMuscle, SkeletalReference ValuesRestHormones

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.