Evidence map›Paper›PMID 29748624›Full record

ArticleScientific reports2018

Cavitation-threshold Determination and Rheological-parameters Estimation of Albumin-stabilized Nanobubbles.

Maxime Lafond, Akiko Watanabe, Shin Yoshizawa, Shin-Ichiro Umemura, Katsuro Tachibana

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cavitation in soft matter.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maxime LafondGraduate School of Biomedical Engineering, Tohoku University, Sendai, Miyagi, 980-8579, Japan. maxime.lafond@gmail.com.ORCID 0000-0001-8954-9099
Akiko WatanabeDepartment of Anatomy, Fukuoka University School of Medicine, Fukuoka, Japan.
Shin YoshizawaGraduate School of Engineering, Tohoku University, Sendai, Miyagi, 980-8579, Japan.
Shin-Ichiro UmemuraGraduate School of Biomedical Engineering, Tohoku University, Sendai, Miyagi, 980-8579, Japan.
Katsuro TachibanaDepartment of Anatomy, Fukuoka University School of Medicine, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanobubbles (NBs) are of high interest for ultrasound (US) imaging as contrast agents and therapy as cavitation nuclei. Because of their instability (Laplace pressure bubble catastrophe) and low sensitivity to US, reducing the size of commonly used microbubbles to submicron-size is not trivial. We introduce stabilized NBs in the 100-250-nm size range, manufactured by agitating human serum albumin and perfluoro-propane. These NBs were exposed to 3.34- and 5.39-MHz US, and their sensitivity to US was proven by detecting inertial cavitation. The cavitation-threshold information was used to run a numerical parametric study based on a modified Rayleigh-Plesset equation (with a Newtonian rheology model). The determined values of surface tension ranged from 0 N/m to 0.06 N/m. The corresponding values of dilatational viscosity ranged from 5.10

Indexed as

MicrobubblesPhysical PhenomenaAlbuminsContrast MediaDrug StabilityHumansManufactured MaterialsMicrotechnologyParticle SizeRheologyStatistics as TopicSurface TensionUltrasonicsViscosityAlbuminsContrast Media

Identifiers

PMID29748624
PMCPMC5945894

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.