ArticleScientific reports2018
Altered attentional control over the salience network in complex regional pain syndrome.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
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- Post-stroke spasticity: advances in network mechanisms and therapeutics.Frontiers in human neuroscience · 2026Review
- Altered brain dynamics in chronic neck and shoulder pain revealed by hidden Markov model.Scientific reports · 2025Article
- Multiple patterns of EEG parameters and their role in the prediction of patients with prolonged disorders of consciousness.Frontiers in neuroscience · 2025Article
- A novel theta-controlled vibrotactile brain-computer interface to treat chronic pain: a pilot study.Scientific reports · 2024Article
- The Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research.Current addiction reports · 2024Review
- Chronic pain as an emergent property of a complex system and the potential roles of psychedelic therapies.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Somatotopic disruption of the functional connectivity of the primary sensorimotor cortex in complex regional pain syndrome type 1.Human brain mapping · 2023Article
- A Manifesto in Defense of Pain Complexity: A Critical Review of Essential Insights in Pain Neuroscience.Journal of clinical medicine · 2023Review
- Preoperative resting-state microstate as a marker for chronic pain after breast cancer surgery.Brain and behavior · 2023Article
- Quantitative Dynamic Allodynograph-A Standardized Measure for Testing Dynamic Mechanical Allodynia in Chronic Limb Pain.Sensors (Basel, Switzerland) · 2023Article
- Sex-specific biobehavioral regulation of persistent inflammatory pain by alcohol.Alcohol, clinical & experimental research · 2023Article
- A Comparison of Functional Connectivity in the Human Brainstem and Spinal Cord Associated with Noxious and Innocuous Thermal Stimulation Identified by Means of Functional MRI.Brain sciences · 2023Article
- Aberrant Resting-state Functional Connectivity in Complex Regional Pain Syndrome: A Network-based Statistics Analysis.Experimental neurobiology · 2023Article
- Oral Health-Related Quality of Life among Chinese Chronic Orofacial Pain Patients with Psychological Health Problems: A Moderated Mediation Model.International journal of environmental research and public health · 2023Article
- Modern Principles of Diagnosis and Treatment in Complex Regional Pain Syndrome.Deutsches Arzteblatt international · 2022Article
- Associations of Regional and Network Functional Connectivity With Exercise-Induced Low Back Pain.The journal of pain · 2021Article
- Intrinsic network activity reflects the ongoing experience of chronic pain.Scientific reports · 2021Article
- The Convergent Neuroscience of Affective Pain and Substance Use Disorder.Alcohol research : current reviews · 2021Review
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The degree and salience of pain have been known to be constantly monitored and modulated by the brain. In the case of maladaptive neural responses as reported in centralized pain conditions such as complex regional pain syndrome (CRPS), the perception of pain is amplified and remains elevated even without sustained peripheral pain inputs. Given that the attentional state of the brain greatly influences the perception and interpretation of pain, we investigated the role of the attention network and its dynamic interactions with other pain-related networks of the brain in CRPS. We examined alterations in the intra- and inter-network functional connectivities in 21 individuals with CRPS and 49 controls. CRPS-related reduction in intra-network functional connectivity was found in the attention network. Individuals with CRPS had greater inter-network connectivities between the attention and salience networks as compared with healthy controls. Furthermore, individuals within the CRPS group with high levels of pain catastrophizing showed greater inter-network connectivities between the attention and salience networks. Taken together, the current findings suggest that these altered connectivities may be potentially associated with the maladaptive pain coping as found in CRPS patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.