Evidence map›Paper›PMID 29748557›Full record

ArticleInternational journal of oral science2018

Recombinant amelogenin regulates the bioactivity of mouse cementoblasts in vitro.

Sema S Hakki, S Buket Bozkurt, Emre Türkay, Michel Dard, Nuhan Purali, Werner Götz

Open access · goldAbstract read
In one paragraph

Article in International journal of oral science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Review
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  13. Article
  14. Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?International journal of molecular sciences · 2020
    Review
  15. Adiponectin InteractsFrontiers in pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Sema S HakkiDepartment of Periodontology, Faculty of Dentistry, Selçuk University, 42079, Konya, Turkey. sshakki@yahoo.com.
S Buket BozkurtResearch Center of Dental Faculty, Selçuk University, Konya, Turkey.
Emre TürkayDepartment of Orthodontics, Oral Biology Laboratory, Faculty of Dentistry, University of Bonn, Bonn, Germany.
Michel DardDepartment of Periodontology and Implant Dentistry, College of Dentistry, New York University, New York, NY, USA.
Nuhan PuraliDepartment of Biophysics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Werner GötzDepartment of Orthodontics, Oral Biology Laboratory, Faculty of Dentistry, University of Bonn, Bonn, Germany.
Selçuk University · TRUniversity of Bonn · DEHacettepe University · TRNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amelogenin (AMG) is a cell adhesion molecule that has an important role in the mineralization of enamel and regulates events during dental development and root formation. The purpose of the present study was to investigate the effects of recombinant human AMG (rhAMG) on mineralized tissue-associated genes in cementoblasts. Immortalized mouse cementoblasts (OCCM-30) were treated with different concentrations (0.1, 1, 10, 100, 1000, 10,000, 100,000 ng · mL

Indexed as

Alkaline PhosphataseAmelogeninAnimalsBiomarkersCalcification, PhysiologicCell Adhesion MoleculesCell ProliferationCementogenesisCollagen Type ICore Binding Factor Alpha 1 SubunitGene Expression RegulationIntegrin-Binding SialoproteinIn Vitro TechniquesMiceMicroscopy, ConfocalOsteocalcinAlkaline PhosphataseAmelogeninBiomarkersCell Adhesion Moleculescementum attachment protein, 55-kDaCollagen Type ICore Binding Factor Alpha 1 SubunitIntegrin-Binding SialoproteinOsteocalcinOsteopontinRunx2 protein, mouse

Identifiers

PMID29748557
PMCPMC5966809
OpenAlexW2800524276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.