Evidence map›Paper›PMID 29748439›Full record

ArticleHaematologica2018

Autologous T-cell activation fosters ABT-199 resistance in chronic lymphocytic leukemia: rationale for a combined therapy with SYK inhibitors and anti-CD20 monoclonal antibodies.

Esteban Enrique Elías, María Belén Almejún, Ana Colado, Gregorio Cordini, Maricef Vergara-Rubio, Enrique Podaza, Denise Risnik, María Cabrejo, Horacio Fernández-Grecco, Raimundo Fernando Bezares and 7 more

Open access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Frontiers in oncology · 2021
    Article
  11. Review
  12. Article
  13. Spleen tyrosine kinase (SYK) blocks autophagic Tau degradationThe Journal of biological chemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Esteban Enrique ElíasLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
María Belén AlmejúnLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Ana ColadoLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Gregorio CordiniLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Maricef Vergara-RubioLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Enrique PodazaLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Denise RisnikLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
María CabrejoSanatorio Municipal Dr. Julio Méndez, Argentina.
Horacio Fernández-GreccoSanatorio Municipal Dr. Julio Méndez, Argentina.
Raimundo Fernando BezaresHospital General de Agudos Dr. Teodoro Álvarez, Argentina.
María Del Rosario CustidianoInstituto Alexander Fleming, Argentina.
Julio César Sánchez-ÁvalosInstituto Alexander Fleming, Argentina.
Ángeles VicenteHospital Alemán, Buenos Aires, Argentina.
Gonzalo Martín GarateHospital Alemán, Buenos Aires, Argentina.
Mercedes BorgeLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Mirta GiordanoLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina.
Romina GamberaleLaboratorio de Inmunología Oncológica, Instituto de Medicina Experimental (IMEX)-CONICET-Academia Nacional de Medicina (ANM), Argentina rominagamberale@gmail.com.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARAcademia Nacional de Medicina · ARHospital Alemán · ARInstituto Alexander Fleming · ARFundación Ciencias Exactas y Naturales · ARHospital General de Agudos Dr. TEODORO ALVAREZ · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, NeoplasmLeukemia, Lymphocytic, Chronic, B-CellNeoplasm ProteinsSyk KinaseT-LymphocytesAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBridged Bicyclo Compounds, HeterocyclicFemaleHumansLymphocyte ActivationMaleMiddle AgedProtein Kinase InhibitorsBridged Bicyclo Compounds, HeterocyclicNeoplasm ProteinsProtein Kinase InhibitorsRituximabSulfonamidesSyk KinaseSYK protein, humanvenetoclax

Identifiers

PMID29748439
PMCPMC6165796
OpenAlexW2800873709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.