Evidence map›Paper›PMID 29747887›Full record

ReviewClinics in perinatology2018

Preventing Continuous Positive Airway Pressure Failure: Evidence-Based and Physiologically Sound Practices from Delivery Room to the Neonatal Intensive Care Unit.

Clyde J Wright, Laurie G Sherlock, Rakesh Sahni, Richard A Polin

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Article
  3. Bubble NIPPV: Guidelines for Use.Children (Basel, Switzerland) · 2025
    Article
  4. Decreasing early invasive mechanical ventilation exposure in preterm infants: a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  5. RDS-NExT workshop: consensus statements for the use of surfactant in preterm neonates with RDS.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Early predictors of continuous positive airway pressure failure in preterm neonates.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
  14. Why, when, and how to give surfactant.Pediatric research · 2019
    Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Clyde J WrightSection of Neonatology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Perinatal Research Center, Mail Stop F441, 13243 East 23rd Avenue, Aurora, CO 80045, USA. Electronic address: clyde.wright@ucdenver.edu.
Laurie G SherlockSection of Neonatology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Perinatal Research Center, Mail Stop F441, 13243 East 23rd Avenue, Aurora, CO 80045, USA.
Rakesh SahniDepartment of Pediatrics, NICU, Columbia University College of Physicians and Surgeons, NewYork-Presbyterian Morgan Stanley Children's Hospital, CUMC, 622 West 168th Street, PH 17-112, New York, NY 10032, USA.
Richard A PolinDepartment of Pediatrics, Division of Neonatology, Columbia University College of Physicians and Surgeons, NewYork-Presbyterian Morgan Stanley Children's Hospital, 622 West 168th Street, PH 17-110, New York, NY 10032, USA.
Children's Hospital Colorado · USColumbia University · USMorgan Stanley Children's Hospital · USUniversity of Colorado Denver · US

Funding

Role of hepatic IkBb-mediated sustained NFkB activation in neonatal lung injury and abnormal developmentR01HL132941 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI WRIGHT, CLYDE JASON · 2017 to 2021
$2.3M
The unique role of IkBa in modulating NF-kB activity in the newborn lung.K08HL098562 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI WRIGHT, CLYDE JASON · 2010 to 2014
$670k
NHLBI NIH HHS K08 HL098562NHLBI NIH HHS R01 HL132941
6 · The paper itself

Abstract

Routine use of continuous positive airway pressure (CPAP) to support preterm infants with respiratory distress is an evidenced-based strategy to decrease incidence of bronchopulmonary dysplasia. However, rates of CPAP failure remain unacceptably high in very premature neonates, who are at high risk for developing bronchopulmonary dysplasia. Using the GRADE framework to assess the quality of available evidence, this article reviews strategies aimed at decreasing CPAP failure, starting with delivery room interventions and followed through to system-based efforts in the neonatal intensive care unit. Despite best efforts, some very premature neonates fail CPAP. Also reviewed are predictors of CPAP failure in this vulnerable population.

Indexed as

Infant, PrematureTreatment FailureAdultBronchopulmonary DysplasiaContinuous Positive Airway PressureDelivery RoomsEvidence-Based MedicineFemaleGestational AgeHumansIntensive Care Units, NeonatalMalePredictive Value of TestsPregnancyPrimary PreventionRandomized Controlled Trials as TopicBronchopulmonary dysplasiaContinuous positive airway pressureInfant flow driverINSUREMechanical ventilationRandomized controlled trialSustained lung inflationVentilatory-induced lung injury

Identifiers

PMID29747887
PMCPMC5953203
OpenAlexW2787986883

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.