Evidence map›Paper›PMID 29747706›Full record

Trial reportPsychological medicine2019

Does online insomnia treatment reduce depressive symptoms? A randomized controlled trial in individuals with both insomnia and depressive symptoms.

T van der Zweerde, A van Straten, M Effting, S D Kyle, J Lancee

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 114 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

T van der ZweerdeDepartment of Clinical Psychology & EMGO Institute for Health and Care Research, VU University,Amsterdam,The Netherlands.ORCID 0000-0001-9443-1757
A van StratenDepartment of Clinical Psychology & EMGO Institute for Health and Care Research, VU University,Amsterdam,The Netherlands.ORCID 0000-0001-6875-2215
M EfftingDepartment of Clinical Psychology,University of Amsterdam,Amsterdam,The Netherlands.
S D KyleSleep and Circadian Neuroscience Institute, University of Oxford,Oxford,UK.ORCID 0000-0002-9581-5311
J LanceeDepartment of Clinical Psychology,University of Amsterdam,Amsterdam,The Netherlands.ORCID 0000-0002-7722-5780
Amsterdam Public Health · NLAmsterdam University of Applied Sciences · NLUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsomnia is effectively treated with online Cognitive Behavioral Therapy for Insomnia (CBT-I). Previous research has suggested the effects might not be limited to sleep and insomnia severity, but also apply to depressive symptoms. Results, however, are mixed.

methodsIn this randomized controlled trial we investigated the effects of guided online CBT-I on depression and insomnia in people suffering from symptoms of both. Participants (n = 104) with clinical insomnia and at least subclinical depression levels were randomized to (1) guided online CBT-I and sleep diary monitoring (i-Sleep) or (2) control group (sleep diary monitoring only). The primary outcome was the severity of depressive symptoms (Patient Health Questionnaire-9 without sleep item; PHQ-WS). Secondary outcomes were insomnia severity, sleep diary parameters, fatigue, daytime consequences of insomnia, anxiety, and perseverative thinking.

resultsAt post-test, participants in the i-Sleep condition reported significantly less depressive symptoms (PHQ-WS) compared with participants in the sleep-diary condition (d = 0.76). Large significant effects were also observed for insomnia severity (d = 2.36), most sleep diary parameters, daytime consequences of insomnia, anxiety, and perseverative thinking. Effects were maintained at 3 and 6 month follow-up. We did not find significant post-test effects on fatigue or total sleep time.

conclusionsFindings indicate that guided online CBT-I is not only effective for insomnia complaints but also for depressive symptoms. The effects are large and comparable with those of depression therapy. CLINICAL TRIAL REGISTRATION NUMBER: NTR6049 (Netherlands Trial Register).

Indexed as

AdultAgedCognitive Behavioral TherapyDepressionFemaleHealth Status IndicatorsHumansInternetMaleMiddle AgedNetherlandsRegression AnalysisSleep Initiation and Maintenance DisordersTelemedicineTreatment Adherence and ComplianceTreatment OutcomeCBTdepressioninsomniaonline treatmentrandomized controlled trial

Identifiers

PMID29747706
PMCPMC6331685
OpenAlexW2802493779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.