ArticleBMC psychiatry2018
Evaluation of a multimodal school-based depression and suicide prevention program among Dutch adolescents: design of a cluster-randomized controlled trial.
Article in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Risk Factors Addressed in Programs for the Prevention of Child and Adolescent Suicide in the School Setting: A Systematic Review.Actas espanolas de psiquiatria · 2025Pooled it
- Prevention of self-harm and suicide in young people up to the age of 25 in education settings.The Cochrane database of systematic reviews · 2024Pooled it
- Educational agents and institutions called into action in suicide prevention, intervention, and postvention.Frontiers in psychology · 2023Pooled it
- Trial
- Trihexyphenidyl Ameliorates Depression-like Behaviors in Adult Zebrafish Exposed to Chronic Unpredictable Stress, Consistent with Regulation of the MAPK Signaling Pathway.Biomolecules · 2026Article
- Multimodal prediction of future depressive symptoms in adolescents.BMC psychiatry · 2025Article
- Multimodal Prediction of Future Depressive Symptoms in Adolescents.Research square · 2025Article
- Effects of binaural beat therapy with different frequencies on autonomic nervous system regulation among college students.BMC complementary medicine and therapies · 2025Article
- Suicide prevention program on suicidal behaviors and mental wellbeing among school aged adolescents: a scoping review.Frontiers in public health · 2025Article
- Investigating the use of support in secondary school: the role of self-reliance and stigma towards help-seeking.Journal of mental health (Abingdon, England) · 2024Article
- A comparison of the effectiveness of cognitive behavioural interventions based on delivery features for elevated symptoms of depression in adolescents: A systematic review.Campbell systematic reviews · 2024Review
- Development of an implementation plan for a school-based multimodal approach for depression and suicide prevention in adolescents.Frontiers in public health · 2024Article
- Risk and protective factors associated with mental health status in an Italian sample of students during the fourth wave of COVID-19 pandemic.Child and adolescent psychiatry and mental health · 2023Article
- Closing the gap between screening and depression prevention: a qualitative study on barriers and facilitators from the perspective of public health professionals in a school-based prevention approach.BMC public health · 2023Article
- Supporting Adolescents with Mental Health Problems in Secondary Education: Feasibility of a Supported Education Intervention.International journal of environmental research and public health · 2022Article
- An integrated community mental healthcare program to reduce suicidal ideation and improve maternal mental health during the postnatal period: the findings from the Nagano trial.BMC psychiatry · 2020Article
- Does Interpersonal Interaction Really Improve Emotion, Sleep Quality, and Self-Efficacy among Junior College Students?International journal of environmental research and public health · 2020Article
- Article
- Relationships between depression, health‑related behaviors, and internet addiction in female junior college students.PloS one · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince 2010, suicide has been the most important cause of mortality in youth aged 15 to 29 years in the Netherlands. Depression is an important risk factor for suicidal behaviors (i.e., suicide ideation, deliberate self-harm, planning, and suicide attempts) in adolescents. Adolescents who develop depressive symptoms, are also at risk for adult depression. This developmental continuity is especially noticeable in adolescents compared to other age groups; therefore, it is necessary to develop preventive strategies for teens. This study will test a multimodal school-based approach to suicide and depression prevention, which integrates universal and targeted approaches and includes various stakeholders (schools, adolescents, parents, and mental health professionals) simultaneously.
methodsWe will perform a cluster randomized controlled trial (RCT) with an intervention and control condition to test the effectiveness of a school-based multimodal stepped-prevention program for depression and suicidal behaviors in adolescents. Adolescents in their second year of secondary education will participate in the study. The participants in the intervention condition will receive the entire multimodal stepped-preventive program comprising early screening and detection of suicidal behaviors and depressive symptoms, a safety net consisting of gatekeepers at school, followed by universal and indicated prevention. The participants in the control condition will undergo only the screening and the safety net of gatekeepers at schools. They will complete assessments at baseline, post-intervention, and 6, 12, and 24-month follow-up. Primary outcome will be suicidal behaviors measured at 12-months follow-up. Additionally, the present study will identify mechanisms that mediate and moderate the program effects and test the effect of the program on various secondary outcomes. DISCUSSION: If the school-based multimodal stepped-prevention program proves to be effective, it could be implemented in schools on a large scale.
trial registrationThe study is registered in the Dutch Trial Register ( NTR6622 ).
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