ArticleBMC genomics2018
Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 59 citations in OpenAlex.
- Role ofJournal of fungi (Basel, Switzerland) · 2026Article
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- ZipV Is Required for Oxidative Stress Resistance and Pathogenicity inJournal of fungi (Basel, Switzerland) · 2026Article
- A long non-coding RNA,bioRxiv : the preprint server for biology · 2026Article
- Plant recognition by Trichoderma Harzianum elicits upregulation of a novel secondary metabolite cluster required for colonization.Scientific reports · 2026Article
- The MeaB bZIP transcription factor is needed for proper nitrosative stress response induced by nitrite in Aspergillus fumigatus.BMC genomics · 2025Article
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- Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence.BMC biology · 2025Article
- Resynthesis of Damaged Fe-S Cluster Proteins ProtectsJournal of fungi (Basel, Switzerland) · 2024Article
- The Oxidative Stress Response Highly Depends on Glucose and Iron Availability inJournal of fungi (Basel, Switzerland) · 2024Article
- Article
- The Transcriptome Response to Azole Compounds inJournal of fungi (Basel, Switzerland) · 2023Article
- Stress Responses Elicited by Glucose Withdrawal inJournal of fungi (Basel, Switzerland) · 2022Article
- Secretion of the siderophore rhizoferrin is regulated by the cAMP-PKA pathway and is involved in the virulence of Mucor lusitanicus.Scientific reports · 2022Article
- Biologia futura: combinatorial stress responses in fungi.Biologia futura · 2022Review
- Assessing Differences between Clinical Isolates ofPathogens (Basel, Switzerland) · 2022Article
- Superoxide Dismutases in Eukaryotic Microorganisms: Four Case Studies.Antioxidants (Basel, Switzerland) · 2022Review
- Strategies Shaping the Transcription of Carbohydrate-Active Enzyme Genes inJournal of fungi (Basel, Switzerland) · 2022Article
- Ambient Availability of Amino Acids, Proteins, and Iron Impacts Copper Resistance ofFrontiers in cellular and infection microbiology · 2022Article
- Research on the Oxidative Stress Response of Human Body Caused by Different Nutritional Supplements and the Improvement Effect of Exercise.Computational intelligence and neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundAspergillus fumigatus has to cope with a combination of several stress types while colonizing the human body. A functional interplay between these different stress responses can increase the chances of survival for this opportunistic human pathogen during the invasion of its host. In this study, we shed light on how the H
resultsThe applied H
conclusionsOur data demonstrate that studying stress responses under separate single stress conditions is not sufficient to understand how A. fumigatus adapts in a complex and hostile habitat like the human body. The combinatorial stress of iron depletion and hydrogen peroxide caused clear non-additive effects upon the stress response of A. fumigatus. Our data further supported the view that the ability of A. fumigatus to cause diseases in humans strongly depends on its fitness attributes and less on specific virulence factors. In summary, A. fumigatus is able to mount and coordinate complex and efficient responses to combined stresses like iron deprivation plus H
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.