ArticleBMC genomics2018
Global evolution and phylogeography of Brucella melitensis strains.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 58 citations in OpenAlex.
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- Distribution and epidemiology of brucellosis in China.Veterinary research communications · 2026Review
- Isolation of Brucella suis from cattle in India: whole genome analysis unravels potential for zoonotic transmission.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Geographic distribution and genetic diversity of Brucella melitensis from Yunnan province, China.BMC microbiology · 2025Article
- Genomic and spatial heterogeneity of Brucella melitensis underscores latent brucellosis risks in non-endemic zones in Southwest China.Communications biology · 2025Article
- Genomic insights intoMicrobiology spectrum · 2025Article
- Genome phylogenetic analysis of Brucella melitensis in Northwest China.BMC microbiology · 2025Article
- Epidemiological Evolution Profile of Human Brucellosis and Socioeconomic Factor Correlation Analysis - Southern and Northern Areas, China, 1950-2021.China CDC weekly · 2025Article
- Global Species/Biovars and Genotype Diversity Atlas ofChina CDC weekly · 2025Article
- Retrospective Analysis of the Epidemiological Evolution of Brucellosis in Animals - China, 1951-1989 and 1996-2021.China CDC weekly · 2024Article
- Whole-genome sequencing-based analysis of Brucella species isolated from ruminants in various regions of Türki̇ye.BMC infectious diseases · 2024Article
- Molecular typing methods to characterizeVeterinary world · 2024Review
- MultipleFrontiers in cellular and infection microbiology · 2024Article
- Article
- Genotype diversity of brucellosis agents isolated from humans and animals in Greece based on whole-genome sequencing.BMC infectious diseases · 2023Article
- A 14th century CE Brucella melitensis genome and the recent expansion of the Western Mediterranean clade.PLoS pathogens · 2023Article
- Whole-genome sequencing for genetic diversity analysis of IranianOne health (Amsterdam, Netherlands) · 2023Article
- Global phylogenomic diversity ofFrontiers in microbiology · 2023Article
- Native circulatingFrontiers in microbiology · 2023Article
- First record of the human infection of Brucella melitensis in Kyrgyzstan: evidence from whole-genome sequencing-based analysis.Infectious diseases of poverty · 2022Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBrucellosis is a bacterial zoonotic disease. Annually in the world more than 500,000 new cases of brucellosis in humans are registered. In this study, we propose an evolutionary model of the historical distribution of B. melitensis based on the full-genomic SNP analysis of 98 strains.
resultsWe performed an analysis of the SNP of the complete genomes of 98 B. melitensis strains isolated in different geographical regions of the world to obtain relevant information on the population structure, genetic diversity and the evolution history of the species. Using genomic sequences of 21 strains of B. melitensis isolated in Russia and WGS data from the NCBI database, it was possible to identify five main genotypes and 13 species genotypes for analysis. Data analysis based on the Bayesian Phylogenetics and Phylogeography method allowed to determine the regions of geographical origin and the expected pathways of distribution of the main lines (genotypes and subgenotypes) of the pathogen.
conclusionsWithin the framework of our study, the model of global evolution and phylogeography of B. melitensis strains isolated in various regions of the planet was proposed for the first time. The sets of unique specific SNPs described in our study, for all identified genotypes and subgenotypes, can be used to develop new bacterial typing and identification systems for B. melitensis.
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