Evidence map›Paper›PMID 29747466›Full record

ReviewInternational journal of molecular sciences2018

An aPPARent Functional Consequence in Skeletal Muscle Physiology via Peroxisome Proliferator-Activated Receptors.

Wendy Wen Ting Phua, Melissa Xin Yu Wong, Zehuan Liao, Nguan Soon Tan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 73 citations in OpenAlex.

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  14. International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Wendy Wen Ting PhuaSchool of Biological Sciences, Nanyang Technological University 60 Nanyang Drive, Singapore 637551, Singapore. wphua003@e.ntu.edu.sg.
Melissa Xin Yu WongSchool of Biological Sciences, Nanyang Technological University 60 Nanyang Drive, Singapore 637551, Singapore. mwong018@e.ntu.edu.sg.
Zehuan LiaoSchool of Biological Sciences, Nanyang Technological University 60 Nanyang Drive, Singapore 637551, Singapore. liao0058@e.ntu.edu.sg.
Nguan Soon TanSchool of Biological Sciences, Nanyang Technological University 60 Nanyang Drive, Singapore 637551, Singapore. nstan@ntu.edu.sg.ORCID 0000-0003-0136-7341
Nanyang Technological University · SGAgency for Science, Technology and Research · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle comprises 30⁻40% of the total body mass and plays a central role in energy homeostasis in the body. The deregulation of energy homeostasis is a common underlying characteristic of metabolic syndrome. Over the past decades, peroxisome proliferator-activated receptors (PPARs) have been shown to play critical regulatory roles in skeletal muscle. The three family members of PPAR have overlapping roles that contribute to the myriad of processes in skeletal muscle. This review aims to provide an overview of the functions of different PPAR members in energy homeostasis as well as during skeletal muscle metabolic disorders, with a particular focus on human and relevant mouse model studies.

Indexed as

AgingAnimalsDiabetes Mellitus, Type 2ExerciseHumansInsulin ResistanceLipid MetabolismMetabolic SyndromeMiceMuscle, SkeletalMuscular DiseasesPeroxisome Proliferator-Activated ReceptorsPhysical Conditioning, AnimalPeroxisome Proliferator-Activated Receptorsaginginsulin resistancelipid metabolismmuscle regenerationperoxisome proliferator-activated receptorphysical exerciseskeletal muscletype 2 diabetes

Identifiers

PMID29747466
PMCPMC5983589
OpenAlexW2802369867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.