Evidence map›Paper›PMID 29747449›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Iron Oxide Colloidal Nanoclusters as Theranostic Vehicles and Their Interactions at the Cellular Level.

Athanasia Kostopoulou, Konstantinos Brintakis, Eirini Fragogeorgi, Amalia Anthousi, Liberato Manna, Sylvie Begin-Colin, Claire Billotey, Anthi Ranella, George Loudos, Irene Athanassakis and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Magnetic Nanoparticle Composites: Synergistic Effects and Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Athanasia KostopoulouInstitute of Electronic Structure and Laser, Foundation for the Research and Technology, Hellas, Vassilika Vouton, 711 10 Heraklion, Greece. akosto@iesl.forth.gr.
Konstantinos BrintakisInstitute of Electronic Structure and Laser, Foundation for the Research and Technology, Hellas, Vassilika Vouton, 711 10 Heraklion, Greece. kbrin@iesl.forth.gr.ORCID 0000-0003-0290-9237
Eirini FragogeorgiInstitute of Nuclear & Radiological Sciences, Technology, Energy & Safety, NCSR "Demokritos", 153 41 Aghia Paraskevi, Athens, Greece. fragkogeorgi@rrp.demokritos.gr.
Amalia AnthousiDepartment of Biology, University of Crete, Vassilika Vouton, 710 03 Heraklion, Greece. Amalia.Anthousi@lstmed.ac.uk.
Liberato MannaIstituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy. liberato.manna@iit.it.
Sylvie Begin-ColinUniversité de Strasbourg, CNRS, Institut de Physique et Chimie des Matériaux de Strasbourg, UMR 7504, F-67034 Strasbourg, France. sylvie.begin@ipcms.unistra.fr.
Claire BilloteyUniversité de Lyon, Université Jean Monnet, EA 3738, Ciblage Thérapeutique en Oncologie, UJM-UCBL-HCL, Hôpital E. Herriot, 5 place d'Arsonval, 69437 Lyon CEDEX 03, France. claire.billotey@univ-st-etienne.fr.
Anthi RanellaInstitute of Electronic Structure and Laser, Foundation for the Research and Technology, Hellas, Vassilika Vouton, 711 10 Heraklion, Greece. ranthi@iesl.forth.gr.
George LoudosBioemission Technology Solutions, Alexandras 116, 117 42 Athens, Greece. gloudos@teiath.gr.
Irene AthanassakisDepartment of Biology, University of Crete, Vassilika Vouton, 710 03 Heraklion, Greece. athan@biology.uoc.gr.
Alexandros LappasInstitute of Electronic Structure and Laser, Foundation for the Research and Technology, Hellas, Vassilika Vouton, 711 10 Heraklion, Greece. lappas@iesl.forth.gr.ORCID 0000-0001-8486-0312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in surfactant-assisted chemical approaches have led the way for the exploitation of nanoscale inorganic particles in medical diagnosis and treatment. In this field, magnetically-driven multimodal nanotools that perform both detection and therapy, well-designed in size, shape and composition, are highly advantageous. Such a theranostic material—which entails the controlled assembly of smaller (maghemite) nanocrystals in a secondary motif that is highly dispersible in aqueous media—is discussed here. These surface functionalized, pomegranate-like ferrimagnetic nanoclusters (40⁻85 nm) are made of nanocrystal subunits that show a remarkable magnetic resonance imaging contrast efficiency, which is better than that of the superparamagnetic contrast agent Endorem

Indexed as

cell interactionsimmune systemmagnetic nanoclustersMRI contrast agentsmulticore particle assemblynanoparticle biodistributionscintigraphic imaging

Identifiers

PMID29747449
PMCPMC5977329

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.