Evidence map›Paper›PMID 29747390›Full record

ReviewMolecules (Basel, Switzerland)2018

Functional Aspects of Fish Mucosal Lectins-Interaction with Non-Self.

Monica Fengsrud Brinchmann, Deepti Manjari Patel, Nevil Pinto, Martin Haugmo Iversen

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Monica Fengsrud BrinchmannFaculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway. monica.f.brinchmann@nord.no.ORCID 0000-0002-1222-0743
Deepti Manjari PatelFaculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway. deepti.m.patel@nord.no.
Nevil PintoFaculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway. nevilpinto1@gmail.com.
Martin Haugmo IversenFaculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway. martin.h.iversen@nord.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal surfaces are of key importance in protecting animals against external threats including pathogens. In the mucosal surfaces, host molecules interact with non-self to prevent infection and disease. Interestingly, both inhibition and stimulation of uptake hinder infection. In this review, the current knowledgebase on teleost mucosal lectins’ ability to interact with non-self is summarised with a focus on agglutination, growth inhibition, opsonisation, cell adhesion, and direct killing activities. Further research on lectins is essential, both to understand the immune system of fishes, since they rely more on the innate immune system than mammals, and also to explore these molecules’ antibiotic and antiparasitic activities against veterinary and human pathogens.

Indexed as

AnimalsBiofilmsChemotaxisFishesHemagglutinationHumansLectinsMucous MembraneLectinsagglutinationantibacterialinnate immunologylectinmucosalphagocytosisteleost

Identifiers

PMID29747390
PMCPMC6100423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.