ArticlePLoS genetics2018
Parallel altitudinal clines reveal trends in adaptive evolution of genome size in Zea mays.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- Selection shapes the evolution of genome size in a globally invasive plant.The New phytologist · 2026Article
- Plastid and nuclear phylogenomics of Cyphostemma (Vitaceae) provide new insights into genome size evolution across sub-Saharan Africa.Journal of integrative plant biology · 2026Article
- A regulatory network underlying glume hardness revealed by transcriptomic analysis of an ems-induced mutant in synthetic hexaploid wheat.BMC genomics · 2026Article
- Intraspecific genome size variation is attributed to adaptive silencing of transposable elements in Hordeum species.Molecular biology and evolution · 2026Article
- Integrating genome size variation, ISSR-derived genetic structure, and phenotypical traits from the Southern Peruvian Andean maize (Frontiers in plant science · 2026Article
- Multi-dimensional identification and quality evaluation ofFrontiers in plant science · 2026Article
- Tracing the global spread of maize (Zea mays L.) through plastome analysis of landraces.BMC plant biology · 2025Article
- Domestication shaped the chromatin landscape of grain amaranth.Nature communications · 2025Article
- Small Genome Size Ensures Adaptive Flexibility for an Alpine Ginger.Genome biology and evolution · 2025Article
- Genetic and environmental influences on the distributions of three chromosomal drive haplotypes in maize.PLoS genetics · 2025Article
- Repeat competition and ecological shifts drive the evolution of the mobilome in Rhynchospora Vahl (Cyperaceae), the holocentric beaksedges.Annals of botany · 2025Article
- Maize B chromosome affects the flowering time.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genome Size Variation inGenes · 2024Article
- Genome size variation and evolution during invasive range expansion in an introduced plant.Evolutionary applications · 2024Article
- LocoGSE, a sequence-based genome size estimator for plants.Frontiers in plant science · 2024Article
- Quantifying the role of genome size and repeat content in adaptive variation and the architecture of flowering time in Amaranthus tuberculatus.PLoS genetics · 2023Article
- Endoreplication-Why Are We Not Using Its Full Application Potential?International journal of molecular sciences · 2023Review
- Three recent sex chromosome-to-autosome fusions in a Drosophila virilis strain with high satellite DNA content.Genetics · 2023Article
- Genome size variation withinEcology and evolution · 2023Article
- Genomic C-Value Variation Analysis in Jujube (Plants (Basel, Switzerland) · 2023Article
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
While the vast majority of genome size variation in plants is due to differences in repetitive sequence, we know little about how selection acts on repeat content in natural populations. Here we investigate parallel changes in intraspecific genome size and repeat content of domesticated maize (Zea mays) landraces and their wild relative teosinte across altitudinal gradients in Mesoamerica and South America. We combine genotyping, low coverage whole-genome sequence data, and flow cytometry to test for evidence of selection on genome size and individual repeat abundance. We find that population structure alone cannot explain the observed variation, implying that clinal patterns of genome size are maintained by natural selection. Our modeling additionally provides evidence of selection on individual heterochromatic knob repeats, likely due to their large individual contribution to genome size. To better understand the phenotypes driving selection on genome size, we conducted a growth chamber experiment using a population of highland teosinte exhibiting extensive variation in genome size. We find weak support for a positive correlation between genome size and cell size, but stronger support for a negative correlation between genome size and the rate of cell production. Reanalyzing published data of cell counts in maize shoot apical meristems, we then identify a negative correlation between cell production rate and flowering time. Together, our data suggest a model in which variation in genome size is driven by natural selection on flowering time across altitudinal clines, connecting intraspecific variation in repetitive sequence to important differences in adaptive phenotypes.
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