Evidence map›Paper›PMID 29746340›Full record

GuidelineJournal of pediatric gastroenterology and nutrition2018

Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood: Consensus From INSPPIRE.

Isabelle Scheers, Joseph J Palermo, Steven Freedman, Michael Wilschanski, Uzma Shah, Maisam Abu-El-Haija, Bradley Barth, Douglas S Fishman, Cheryl Gariepy, Matthew J Giefer and 18 more

Registry-linked trialOpen access · greenAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Journal of pediatric gastroenterology and nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03672422 (Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03672422 completednot on this map

Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC) CPDPC16-03 Pediatric Longitudinal Cohort Study of Chronic Pancreatitis

Typeobservational_patient_registrySponsorAliye UcRan2017 to 2020Enrolled623ConditionsPancreatitis, Chronic, Pancreatitis, AcuteArmsBlood sample, Patient questionnaires, Saliva sample, Urine sample
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Autoimmune Pancreatitis Type 2, Biliary Cysts andChildren (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Autoimmune Pancreatitis in an Adolescent: A Diagnostic Challenge.GE Portuguese journal of gastroenterology · 2020
    Article
  14. Pancreatitis in Children.Gastroenterology · 2019
    Review
  15. A Review of MicroRNA Biomarkers in Traumatic Brain Injury.Journal of experimental neuroscience · 2019
    Review
  16. Article
  17. Article
  18. Article
  19. EUS in pediatric patients.Endoscopic ultrasound
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 19 institutions in 4 countries.

Isabelle ScheersHospital for Sick Children, Toronto, Ontario, Canada.
Joseph J PalermoCincinnati Children's Hospital Medical Center, Cincinnati, OH.
Steven FreedmanHarvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA.
Michael WilschanskiHadassah Hebrew University Hospital, Jerusalem, Israel.
Uzma ShahHarvard Medical School, Massachusetts General Hospital for Children, Boston, MA.
Maisam Abu-El-HaijaCincinnati Children's Hospital Medical Center, Cincinnati, OH.
Bradley BarthUniversity of Texas Southwestern Medical School, Dallas.
Douglas S FishmanBaylor College of Medicine, Houston, TX.
Cheryl GariepyNationwide Children's Hospital, Columbus, OH.
Matthew J GieferSeattle Children's Hospital, Seattle, WA.
Melvin B HeymanUniversity of California at San Francisco, San Francisco, CA.
Ryan W HimesBaylor College of Medicine, Houston, TX.
Sohail Z HusainChildren's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.
Tom K LinCincinnati Children's Hospital Medical Center, Cincinnati, OH.
Quin LiuCedars-Sinai Medical Center, Los Angeles, CA.
Mark LoweWashington University School of Medicine, St-Louis, MO.
Maria MascarenhasThe Children's Hospital of Philadelphia, Philadelphia, PA.
Veronique MorinvilleMontreal Children's Hospital, McGill University, Montreal, QC, Canada.
Chee Y OoiDiscipline of Paediatrics, School of Women's and Children's Health Medicine, University of New South Wales and Sydney Children's Hospital Randwick, Sydney, Australia.
Emily R PeritoUniversity of California at San Francisco, San Francisco, CA.
David A PiccoliThe Children's Hospital of Philadelphia, Philadelphia, PA.
John F PohlUniversity of Utah, Salt Lake City, UT.
Sarah J SchwarzenbergUniversity of Minnesota, Masonic Children's Hospital, Minneapolis, MN.
David TroendleUniversity of Texas Southwestern Medical School, Dallas.
Steven WerlinMedical College of Wisconsin, Milwaukee, WI.
Bridget ZimmermanUniversity of Iowa, Carver College of Medicine, Iowa City, IA.
Aliye UcUniversity of Iowa, Carver College of Medicine, Iowa City, IA.
Tanja GonskaHospital for Sick Children, Toronto, Ontario, Canada.
Cincinnati Children's Hospital Medical Center · USBaylor College of Medicine · USChildren's Hospital of Philadelphia · USThe University of Texas Southwestern Medical Center · USUniversity of Iowa · USCedars-Sinai Medical Center · USChildren's Hospital of Pittsburgh · USCliniques Universitaires Saint-Luc · BEHarvard University · USHospital for Sick Children · CAMassachusetts General Hospital · USMcGill University · CAMedical College of Wisconsin · USNationwide Children's Hospital · USSeattle Children's Hospital · USUniversity of Minnesota Children's Hospital · USUniversity of Utah · USUNSW Sydney · AUWashington University in St. Louis · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Year 9 Administrative Supplement to INSPPIRE 2U01DK108334 · NIDDK · UNIVERSITY OF IOWA · PI MARK E. LOWE, Aliye Uc · 2015 to 2026
$10.5M
University of Iowa Clinical and Translational Science ProgramUL1TR000442 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2012 to 2013
$10.0M
DYSBIOTIC MICROBIOME IN PANCREATITIS, DIABETES, AND PANCREATIC CANCERU01DK108326 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI FISHER, WILLIAM E · 2015 to 2024
$5.2M
Fatty Acid Defects & Oxidative Stress Modulate Islet Function in Cystic FibrosisR01DK097820 · NIDDK · UNIVERSITY OF IOWA · PI NORRIS, ANDREW W, UC, ALIYE · 2012 to 2016
$1.9M
INSPPIRE TO STUDY ACUTE RECURRENT AND CHRONIC PANCREATITIS IN CHILDRENR21DK096327 · NIDDK · UNIVERSITY OF IOWA · PI UC, ALIYE · 2012 to 2014
$586k
NCATS NIH HHS UL1 TR000442NCATS NIH HHS UL1 TR002538NIDDK NIH HHS P30 DK054759NIDDK NIH HHS R01 DK097820NIDDK NIH HHS R21 DK096327NIDDK NIH HHS U01 DK108326NIDDK NIH HHS U01 DK108334
6 · The paper itself

Abstract

objectivesAutoimmune pancreatitis (AIP) represents a complex immune-mediated pancreas disorder. Pediatric AIP (P-AIP) is rare. We have recently summarized the characteristic features of P-AIP. We now aim to develop recommendation statements to standardize the diagnostic and therapeutic approach to P-AIP and facilitate future research in the field.

methodsA panel of pediatric gastroenterologists participating in the International Study Group of Pediatric Pancreatitis: In search for a cuRE was formed to discuss and then vote on 15 recommendation statements. A consensus of at least 80% was obtained following 3 voting rounds and revision of the statements.

resultsWe have now generated 15 statements to help standardize the approach to diagnosis and management of P-AIP.

conclusionsThe first P-AIP recommendation statements developed by the International Study Group of Pediatric Pancreatitis: In search for a cuRE group are intended to bring standardization to the diagnosis and treatment of this rare childhood disorder. These statements may help guide a uniform approach to patient care and facilitate future research studies.

Indexed as

Autoimmune DiseasesChildHumansPancreatitis

Identifiers

PMID29746340
PMCPMC6059991
OpenAlexW2800295186

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.