Evidence map›Paper›PMID 29745890›Full record

ArticleClinical and experimental rheumatology

Pattern of muscle involvement in inclusion body myositis: a sonographic study.

Jemima Albayda, Lisa Christopher-Stine, Clifton O Bingham Iii, Julie J Paik, Eleni Tiniakou, Seth Billings, O Manny Uy, Philippe Burlina

Open access · greenAbstract readComparative Study
PubMed Full text at PMC
In one paragraph

Article in Clinical and experimental rheumatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jemima AlbaydaJohns Hopkins University, School of Medicine, Baltimore, MD, USA. jalbayd1@jhmi.edu.
Lisa Christopher-StineJohns Hopkins University, School of Medicine, Baltimore, MD, USA.
Clifton O Bingham IiiJohns Hopkins University, School of Medicine, Baltimore, MD, USA.
Julie J PaikJohns Hopkins University, School of Medicine, Baltimore, MD, USA.
Eleni TiniakouJohns Hopkins University, School of Medicine, Baltimore, MD, USA.
Seth BillingsJohns Hopkins University, Applied Physics Laboratory, Laurel, MD, USA.
O Manny UyJohns Hopkins University, Applied Physics Laboratory, Laurel, MD, USA.
Philippe BurlinaJohns Hopkins University, Applied Physics Laboratory, Laurel, MD, USA.
Johns Hopkins Medicine · USJohns Hopkins University Applied Physics Laboratory · USJohns Hopkins University · US

Funding

Sample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Antony Rosen · 2016 to 2026
$8.9M
Phenotype-Specific Immune Responses in the Systemic VasculitidesP30AR053503 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ROSEN, ANTONY · 2006 to 2015
$6.4M
NIAMS NIH HHS P30 AR053503NIAMS NIH HHS P30 AR070254
6 · The paper itself

Abstract

objectivesImaging plays a role in myositis assessment by detecting muscle changes indicative of pathology. This study was conducted to determine the ultrasonographic pattern of muscle involvement in patients with inclusion body myositis (IBM) through an assessment of muscle echointensity.

methodsSixty-two individuals were consecutively studied, 18 with IBM, 16 with polymyositis or dermatomyositis and 28 normal controls. Standardised scans were completed bilaterally for the deltoids, biceps, flexor digitorum profundus (FDP), flexor carpi ulnaris, rectus femoris, tibialis anterior and gastrocnemius assessing for muscle echointensity changes.

resultsPatients with IBM had a markedly increased muscle echointensity when compared with comparator groups for all muscles studied. This was most discriminating at the FDP, gastrocnemius and rectus femoris. Asymmetry between sides and a heterogeneously increased echointensity were also seen.

conclusionsUltrasonography can aid in the assessment of IBM by displaying an increased echointensity in characteristically involved muscles, particularly when combined with assessments for asymmetry and echotexture.

Indexed as

AgedAged, 80 and overCase-Control StudiesFemaleHumansMaleMiddle AgedMuscle, SkeletalMyositis, Inclusion BodyPredictive Value of TestsUltrasonography

Identifiers

PMID29745890
PMCPMC6558657
OpenAlexW2924523201

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.