Evidence map›Paper›PMID 29745380›Full record

ArticleJournal of clinical nephrology and renal care2017

The Effect of Chronic Kidney Disease on a Physical Activity Intervention: Impact on Physical Function, Adherence, and Safety.

C K Liu, J Milton, F-C Hsu, K M Beavers, V Yank, T Church, J D Shegog, S Kashaf, S Nayfield, A Newman and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical nephrology and renal care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Pathophysiology and potential treatment of uremic sarcopenia.Kidney research and clinical practice · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

C K LiuNutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer Human Nutrition Research Center in Aging, Tufts University, Boston, MA, USA.
J MiltonBoston University School of Public Health, Boston, MA, USA.
F-C HsuWake Forest School of Medicine, Winston-Salem, NC, USA.
K M BeaversWake Forest School of Medicine, Winston-Salem, NC, USA.
V YankStanford University School of Medicine, Palo Alto, CA, USA.
T ChurchPennington Biomedical Research Center, Baton Rouge, LA, USA.
J D ShegogWake Forest School of Medicine, Winston-Salem, NC, USA.
S KashafYale University School of Medicine, New Haven, CT, USA.
S NayfieldUniversity of Florida College of Medicine, Gainesville, FL, USA.
A NewmanUniversity of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
R S StaffordStanford University School of Medicine, Palo Alto, CA, USA.
B NicklasWake Forest School of Medicine, Winston-Salem, NC, USA.
D E WeinerTufts University School of Medicine, Boston, MA, USA.
R A FieldingNutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer Human Nutrition Research Center in Aging, Tufts University, Boston, MA, USA.
LIFE-P Research Group
Tufts University · US

Funding

UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Ravi Jasuja · 2008 to 2026
$23.9M
Exercise training and cognitive and physical function in CKDR01DK090401 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI SELIGER, STEPHEN L., WEINER, DANIEL E · 2011 to 2014
$2.3M
Mobility of older hemodialysis patientsK23AG057813 · NIA · STANFORD UNIVERSITY · PI LIU, CHRISTINE KEE · 2018 to 2022
$917k
Primary Care eHealth Intervention for Improved Outcomes in Chronic Kidney DiseaseK23DK097308 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YANK, VERONICA · 2013 to 2017
$780k
NIA NIH HHS K23 AG057813NIA NIH HHS L30 AG064790NIA NIH HHS P30 AG031679NIA NIH HHS U01 AG022376NIDDK NIH HHS K23 DK097308NIDDK NIH HHS R01 DK090401
6 · The paper itself

Abstract

backgroundBecause chronic kidney disease (CKD) is associated with muscle wasting, older adults with CKD are likely to have physical function deficits. Physical activity can improve these deficits, but whether CKD attenuates the benefits is unknown. Our objective was to determine if CKD modified the effect of a physical activity intervention in older adults.

methodsThis is an exploratory analysis of the LIFE-P study, which compared a 12-month physical activity program (PA) to a successful aging education program (SA) in older adults. CKD was defined as a baseline eGFR < 60 mL/min/1.73 m

resultsThe sample included 368 participants. CKD was present in 105 (28.5%) participants with a mean eGFR of 49.2 ± 8.1 mL/min/1.73 m

conclusionDespite lower adherence, older adults with CKD likely derive clinically meaningful benefits from physical activity with no apparent impact on safety, compared to those without CKD.

Indexed as

CKDOlder adultsPhysical activitySPPB

Identifiers

PMID29745380
PMCPMC5937279
OpenAlexW2736921279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.