Evidence map›Paper›PMID 29745006›Full record

Trial reportHemodialysis international. International Symposium on Home Hemodialysis2018

Effects of acute intradialytic exercise on cardiovascular responses in hemodialysis patients.

Jin Hee Jeong, Annabel Biruete, Bo Fernhall, Kenneth R Wilund

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Hemodialysis international. International Symposium on Home Hemodialysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06584734 (Effect of Intradialytic Exercise on Left Ventricular Diastolic Function in Hemodialysis Patients), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06584734 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Intradialytic Exercise on Left Ventricular Diastolic Function in Hemodialysis Patients

TypeinterventionalSponsorInstituto Nacional de Cardiologia Ignacio ChavezRan2023 to 2024Enrolled30ConditionsRenal Dialysis, Hemodiafiltration, Diastolic Dysfunction, Kidney FailureArmsNot exercise, Exercise during hemodiafiltration session
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Exercise training for adults undergoing maintenance dialysis.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Guideline
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jin Hee JeongDepartment of Kinesiology and Community Health, Urbana, Illinois, USA.
Annabel BirueteDivision of Nutritional Sciences, University of Illinois, Urbana-Champaign, Urbana, Illinois, USA.
Bo FernhallDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA.
Kenneth R WilundDepartment of Kinesiology and Community Health, Urbana, Illinois, USA.

Funding

MUSCULOSKELETAL TRAINING GRANTT32AR007581 · NIAMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI BURR, DAVID B · 1996 to 2006
$1.4M
NIAMS NIH HHS T32 AR007581
6 · The paper itself

Abstract

backgroundIn patients with kidney failure requiring hemodialysis (HD) treatment, intradialytic exercise (IDEX) has been advocated for its feasibility and effectiveness in improving important health outcomes. However, IDEX as an adjunct therapeutic strategy is infrequently implemented, in part due to potential risks of IDEX, especially in patients with chronic volume overload. This study was performed to evaluate the safety of IDEX performed at different time points by examining its effect on intradialytic cardiovascular hemodynamics.

methodsIn a randomized cross-over study (n = 12), intradialytic changes in brachial, aortic, and cardiac hemodynamics and autonomic function were examined during a HD session; (1) without exercise; (2) with 30 min of IDEX performed in the first hour of treatment; or (3) with 30 min of IDEX in the third hour of treatment.

resultsIDEX during either the first or third hour did not exacerbate hemodynamic instability during treatment regardless of patient's hydrations status. While there were transient increases in stroke volume, cardiac output, and heart rate during IDEX, intradialytic changes in brachial and aortic blood pressure, cardiac hemodynamics, and autonomic function were similar on days with and without IDEX.

conclusionThese results indicate that IDEX does not exacerbate hemodynamic instability during HD, regardless of a patient's hydration status or the timing of exercise.

Indexed as

Blood PressureCross-Over StudiesExerciseFemaleHemodynamicsHumansKidney Failure, ChronicMaleMiddle AgedRenal Dialysisfluid overloadhemodialysishemodynamic stabilityIntradialytic exercise

Identifiers

PMID29745006
PMCPMC10463186

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.