SynthesisAddiction (Abingdon, England)2018
Imaging resilience and recovery in alcohol dependence.
Synthesis in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Structural and functional brain recovery in individuals with substance use disorders during abstinence: A review of longitudinal neuroimaging studies.Drug and alcohol dependence · 2022Pooled it
- Stressful life events are associated with striatal dopamine receptor availability in alcohol dependence.Journal of neural transmission (Vienna, Austria : 1996) · 2019Trial
- Relapse in alcohol dependence is characterized by disrupted modular brain network organization.European archives of psychiatry and clinical neuroscience · 2026Article
- Beyond Stigma-Integrating Neurobiology, Genetics, and Awareness Integration Theory in Addiction Recovery.Psychology research and behavior management · 2026Article
- Advances in Neuroimaging and Deep Learning for Emotion Detection: A Systematic Review of Cognitive Neuroscience and Algorithmic Innovations.Diagnostics (Basel, Switzerland) · 2025Review
- Clinical value of predicting relapse within 3 months in alcohol-dependent patients using fNIRS in verbal fluency task.Scientific reports · 2025Article
- BCI Improves Alcohol-Induced Cognitive and Emotional Impairments by Restoring pERK-BDNF.Journal of molecular neuroscience : MN · 2024Article
- Alcohol use and grey matter structure: Disentangling predispositional and causal contributions in human studies.Addiction biology · 2023Review
- Neurocognitive Recovery in Abstinent Patients with Alcohol Use Disorder: A Scoping Review for Associated Factors.Neuropsychiatric disease and treatment · 2023Article
- Resilience to the effects of social stress on vulnerability to developing drug addiction.World journal of psychiatry · 2022Review
- Classical blood biomarkers identify patients with higher risk for relapse 6 months after alcohol withdrawal treatment.European archives of psychiatry and clinical neuroscience · 2021Article
- Do Social Cognition Deficits Recover with Abstinence in Alcohol-Dependent Patients?Alcoholism, clinical and experimental research · 2021Article
- The Role of the Family in Alcohol Use Disorder Recovery for Adults.Alcohol research : current reviews · 2021Review
- Neurofilament Light Chain Is a Promising Biomarker in Alcohol Dependence.Frontiers in psychiatry · 2021Article
- Association of Prefrontal-Striatal Functional Pathology With Alcohol Abstinence Days at Treatment Initiation and Heavy Drinking After Treatment Initiation.The American journal of psychiatry · 2020Article
- We Need to Delay the Age of Onset of Alcohol Consumption.International journal of environmental research and public health · 2020Article
- Brain-behavior relations and effects of aging and common comorbidities in alcohol use disorder: A review.Neuropsychology · 2019Review
- Role of Patient Sex in Early Recovery from Alcohol-Related Cognitive Impairment: Women Penalized.Journal of clinical medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
aimsResilience and recovery are of increasing importance in the field of alcohol dependence (AD). This paper describes how imaging studies in man can be used to assess the neurobiological correlates of resilience and, if longitudinal, of disease trajectories, progression rates and markers for recovery to inform treatment and prevention options.
methodsOriginal papers on recovery and resilience in alcohol addiction and its neurobiological correlates were identified from PubMed and have been analyzed and condensed within a systematic literature review.
resultsFindings deriving from functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) studies have identified links between increased resilience and less task-elicited neural activation within the basal ganglia, and benefits of heightened neural pre-frontal cortex (PFC) engagement regarding resilience in a broader sense; namely, resilience against relapse in early abstinence of AD. Furthermore, findings consistently propose at least partial recovery of brain glucose metabolism and executive and general cognitive functioning, as well as structural plasticity effects throughout the brain of alcohol-dependent patients during the course of short-, medium- and long-term abstinence, even when patients only lowered their alcohol consumption to a moderate level. Additionally, specific factors were found that appear to influence these observed brain recovery processes in AD, e.g. genotype-dependent neuronal (re)growth, gender-specific neural recovery effects, critical interfering effects of psychiatric comorbidities, additional smoking or marijuana influences or adolescent alcohol abuse.
conclusionsNeuroimaging research has uncovered neurobiological markers that appear to be linked to resilience and improved recovery capacities that are furthermore influenced by various factors such as gender or genetics. Consequently, future system-oriented approaches may help to establish a broad neuroscience-based research framework for alcohol dependence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.