Evidence map›Paper›PMID 29744901›Full record

ArticleBritish journal of clinical pharmacology2018

Hospital readmissions, mortality and potentially inappropriate prescribing: a retrospective study of older adults discharged from hospital.

David Counter, James W T Millar, James S McLay

Abstract read
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Article in British journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Prescribing Practices in Geriatric Patients with Cardiovascular Diseases.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David CounterNHS Grampian, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZB, UK.ORCID 0000-0002-2052-9134
James W T MillarNHS Glasgow and Clyde, Queen Elizabeth University Hospital, Glasgow, G51 4TF, UK.
James S McLayThe Division of Applied Health Sciences, The University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-1120-6704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsApplying version 2 of the STOPP/START criteria to discharge prescriptions of older adults discharged from a general medical unit, the aim of this study is to assess potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) and their association with hospital readmission and mortality.

methodsDischarge medications, co-morbidities and patient demographics were recorded over an 8-month period for consecutive emergency admissions of patients aged ≥65 years. PIMs and PPOs were identified using version 2 of the STOPP/START criteria. Multivariate analysis for association of PIMs and PPOs with re-admissions and mortality during the follow-up period were assessed using binary logistic regression.

resultsData for 259 patients with a mean age of 77 (65-99, 51% female) were analysed. At discharge, the mean number of co-morbidities and medications per patient were 5.4 (SD: 2.1 range: 0-14) and 9.3 (SD: 4.0 range: 1-31) respectively. During the follow-up period (mean 41.5 months, SD: 2.0 range: 38-46 months), 50.2% of patients had died and the median number of readmissions was two (IQR: 1-4 range: 0-33). Prescription of more than five medications was significantly associated with PIMs and PPOs (OR: 2.75, 95% CI: 1.34-5.62 and OR 3.20, 95% CI: 1.57-6.54 respectively). Presence of a PIM was associated with three or more readmissions (OR: 2.43 95% CI: 1.19-4.98) and PPOs with mortality (OR: 1.88, 95% CI: 1.09-3.27).

conclusionsUsing version 2 of the STOPP/START criteria, the presence of PIMs and/or PPOs in older adults discharged from hospital is significantly associated with repeated hospital admissions and mortality respectively.

Indexed as

AftercareAgedAged, 80 and overAge FactorsDrug PrescriptionsFemaleFollow-Up StudiesHumansInappropriate PrescribingMaleMortalityPatient DischargePatient ReadmissionPotentially Inappropriate Medication ListRetrospective Studieshospital admissionmortalityolder adultspotentially inappropriate medicationspotential prescribing omissionsSTOPP/START criteria version 2

Identifiers

PMID29744901
PMCPMC6046509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.