Evidence map›Paper›PMID 29744727›Full record

ReviewEndocrine pathology2018

Immunohistochemical Biomarkers in Thyroid Pathology.

Zubair Baloch, Ozgur Mete, Sylvia L Asa

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Article
  3. Encapsulated neoplasms of the thyroid gland.Virchows Archiv : an international journal of pathology · 2026
    Review
  4. The actual and future role of molecular tests in thyroid pathology.Virchows Archiv : an international journal of pathology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Spectrum of Endocrine Pathology.Endocrine pathology · 2023
    Review
  15. Review
  16. Article
  17. Thyroid Metastasis from Primary Breast Cancer.Journal of clinical medicine · 2023
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Zubair BalochDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Ozgur MeteDepartment of Pathology, Laboratory Medicine Program, University Health Network, Toronto, ON, Canada. ozgur.mete2@uhn.ca.
Sylvia L AsaDepartment of Pathology, Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.
University Health Network · CAUniversity of Pennsylvania · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of immunohistochemistry to the diagnosis of thyroid lesions has increased as new biomarkers have emerged. In this review, we discuss the biomarkers that are critical for accurate diagnosis, prognosis, and management. Immunohistochemical markers are used to confirm that an unusual tumor in the thyroid is indeed of thyroid origin, either of follicular epithelial or C-cell differentiation; the various mimics include nonthyroidal lesions such as parathyroid tumors, paragangliomas, thymic neoplasms, and metastatic malignancies. Tumors of thyroid follicular epithelial cells can be further subclassified using a number of immunohistochemical biomarkers that can distinguish follicular-derived from C-cell lesions and others that support malignancy in borderline cases. The use of mutation-specific antibodies can distinguish papillary carcinomas harboring a BRAF

Indexed as

Biomarkers, TumorHumansImmunohistochemistryThyroid NeoplasmsBiomarkers, TumorBiomarkersImmunohistochemistryThyroid

Identifiers

PMID29744727
OpenAlexW2800204827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.