ArticleEuropean radiology2018
Evaluation of renal lesions using contrast-enhanced ultrasound (CEUS); a 10-year retrospective European single-centre analysis.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Imaging Assessment of Complex Renal Cysts: Comparative Value of Superb Microvascular Imaging and Contrast-Enhanced Ultrasound.Journal of personalized medicine · 2026Article
- Qualitative and Quantitative Analysis of Contrast-Enhanced Ultrasound in the Characterization of Kidney Cancer Subtypes.Diagnostics (Basel, Switzerland) · 2025Article
- Contrast-ultrasound dispersion imaging for renal cell carcinoma diagnostics.The ultrasound journal · 2025Article
- Contrast-enhanced ultrasound of renal masses in the pre-transplant setting: literature review with case highlights.Abdominal radiology (New York) · 2024Review
- Contrast-enhanced ultrasound for differentiating benign from malignant focal solid renal lesions in pediatric patients.Scientific reports · 2024Article
- Improved diagnostic confidence using Super Resolution CEUS imaging in testicular lesions.Clinical hemorheology and microcirculation · 2024Review
- CEUS Bosniak Classification-Time for Differentiation and Change in Renal Cyst Surveillance.Cancers · 2023Review
- Clinical Application Value of Contrast-Enhanced Ultrasound in the Diagnosis of Renal Space-Occupying Lesions.International journal of nephrology and renovascular disease · 2023Article
- Contemporary Clinical Definitions, Differential Diagnosis, and Novel Predictive Tools for Renal Cell Carcinoma.Biomedicines · 2022Review
- Contrast-Enhanced Ultrasound (CEUS) in the Evaluation of Renal Masses with Histopathological Validation-Results from a Prospective Single-Center Study.Diagnostics (Basel, Switzerland) · 2022Article
- Diagnostic Workup for Patients with Solid Renal Masses: A Cost-Effectiveness Analysis.Cancers · 2022Article
- Expanding the Role of Ultrasound for the Characterization of Renal Masses.Journal of clinical medicine · 2022Review
- Contrast-enhanced ultrasound manifestations of renal masses undetectable on conventional ultrasound.Frontiers in oncology · 2022Article
- The added value of contrast-enhanced ultrasound in evaluation of indeterminate small solid renal masses and risk stratification of cystic renal lesions.European radiology · 2021Article
- Diagnostic evaluation and ablation treatments assessment in hepatocellular carcinoma.Infectious agents and cancer · 2021Review
- Imaging findings of primary pulmonary synovial sarcoma with secondary distant metastases: A case report.World journal of clinical cases · 2021Article
- Structured Reporting in the Characterization of Renal Cysts by Contrast-Enhanced Ultrasound (CEUS) Using the Bosniak Classification System-Improvement of Report Quality and Interdisciplinary Communication.Diagnostics (Basel, Switzerland) · 2021Article
- Combining contrast-enhanced ultrasound, CT perfusion andBJR case reports · 2021Article
- Contrast-Enhanced Ultrasound (CEUS) for the Evaluation of Bosniak III Complex Renal Cystic Lesions-A 10-Year Specialized European Single-Center Experience with Histopathological Validation.Medicina (Kaunas, Lithuania) · 2020Article
- Quantification of contrast-uptake as imaging biomarker for disease progression of renal cell carcinoma after tumor ablation.Acta radiologica (Stockholm, Sweden : 1987) · 2020Article
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4 authors.
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Abstract
objectiveTo investigate the usefulness of contrast-enhanced ultrasound (CEUS) in the evaluation of renal masses.
methodsThis study included 255 patients with renal masses. Ages ranged from 18-86 years. CEUS was used for determining malignancy or benignancy and findings were correlated with the histopathological outcome. Out of 255 lesions, 212 lesions were malignant (83.1%) and 43 were benign (16.9%). Diagnostic accuracy was tested using the histopathological diagnosis as the gold standard.
resultsCEUS showed a sensitivity of 99.1% [95% confidence interval (CI): 96.7%, 99.9%], a specificity of 80.5% (CI: 65.1%, 91.2%), a positive predictive value of 96.4% (CI: 93.0%, 98.4%) and a negative predictive value of 94.3% (CI: 80.8%, 99.3%). Kappa for diagnostic accuracy was κ = 0.85 (CI: 0.75, 0.94). Of 212 malignant lesions, 200 renal cell carcinomas and 12 other malignant lesions were diagnosed. Out of 43 benign lesions, 10 angiomyolipomas, 3 oncocytomas, 8 renal cysts and 22 other benign lesions were diagnosed.
conclusionCEUS is an useful method to differentiate between malignant and benignant renal lesions. To date, to our knowledge, this is the largest study in Europe for the evaluation of renal lesions using CEUS with a histopathological validation. KEY POINTS: • CEUS helps clinicians detect and characterise unclear solid and cystic renal lesions • CEUS shows a high diagnostic accuracy in the characterization of these lesions • Proper surgical treatment or follow-up can be given with better diagnostic confidence.
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