Evidence map›Paper›PMID 29744438›Full record

ReviewBioactive materials2018

An overview of graphene-based hydroxyapatite composites for orthopedic applications.

Ming Li, Pan Xiong, Feng Yan, Sijie Li, Changhong Ren, Zhichen Yin, Ang Li, Huafang Li, Xunming Ji, Yufeng Zheng and 1 more

Abstract readReview
In one paragraph

Review in Bioactive materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ming LiChina-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Pan XiongAcademy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Feng YanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Sijie LiBeijing Key Laboratory of Hypoxia Conditioning Translational Medicine, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Changhong RenBeijing Key Laboratory of Hypoxia Conditioning Translational Medicine, Xuanwu Hospital of Capital Medical University, Beijing 100053, China.
Zhichen YinChina-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Ang LiDepartment of Biomedical Engineering, Columbia University, New York, NY 10032, USA.
Huafang LiAcademy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Xunming JiChina-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Yufeng ZhengAcademy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Yan ChengAcademy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxyapatite (HA) is an attractive bioceramic for hard tissue repair and regeneration due to its physicochemical similarities to natural apatite. However, its low fracture toughness, poor tensile strength and weak wear resistance become major obstacles for potential clinical applications. One promising method to tackle with these problems is exploiting graphene and its derivatives (graphene oxide and reduced graphene oxide) as nanoscale reinforcement fillers to fabricate graphene-based hydroxyapatite composites in the form of powders, coatings and scaffolds. The last few years witnessed increasing numbers of studies on the preparation, mechanical and biological evaluations of these novel materials. Herein, various preparation techniques, mechanical behaviors and toughen mechanism, the

Indexed as

Biomedical devicesBone tissueCompositesGrapheneHydroxyapatite

Identifiers

PMID29744438
PMCPMC5935763

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.