ArticleBioactive materials2017
Preliminary focus on the mechanical and antibacterial activity of a PMMA-based bone cement loaded with gold nanoparticles.
Article in Bioactive materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Effect of nanogold incorporation into polymethyl methacrylate denture bases on microbial activity in implant-retained mandibular overdentures.International journal of implant dentistry · 2025Trial
- Gold Nanorod-Doped Acrylic Bone Cement: Mechanical Stability and Feasibility of Photothermal Therapy.Cureus · 2026Article
- Multiscale metal-based nanocomposites for bone and joint disease therapies.Materials today. Bio · 2025Review
- Article
- A review on the promising antibacterial agents in bone cement-From past to current insights.Journal of orthopaedic surgery and research · 2024Review
- Exploring the Relationship between Mechanical Properties and Electrical Impedance in Cement-Based Composites Incorporating Gold Nanoparticles.Materials (Basel, Switzerland) · 2024Article
- Design and characterization of electroactive gelatin methacrylate hydrogel incorporated with gold nanoparticles empowered with parahydroxybenzaldehyde and curcumin for advanced tissue engineering applications.Journal of materials science. Materials in medicine · 2024Article
- Effect of Co-Sputtered Copper and Titanium Oxide Coatings on Bacterial Resistance and Cytocompatibility of Osteoblast Cells.Nanomaterials (Basel, Switzerland) · 2024Article
- Facile fabrication of linezolid/strontium coated hydroxyapatite/graphene oxide nanocomposite for osteoporotic bone defect.Heliyon · 2024Article
- Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles.Nanomaterials (Basel, Switzerland) · 2023Article
- Effect of nanogold particles addition on dimensional stability of complete denture base material: an in - vitro study.BMC oral health · 2023Article
- Application of the Small Punch Creep-Recovery Test (SPCRT) for the Estimation of Large-Amplitude Viscoelastic Properties of Polymers.Materials (Basel, Switzerland) · 2023Article
- Antibacterial Properties of Gold Nanoparticles in the Modification of Medical Implants: A Systematic Review.Pharmaceutics · 2022Review
- Effect of the Antimicrobial Agents Peppermint Essential Oil and Silver Nanoparticles on Bone Cement Properties.Biomimetics (Basel, Switzerland) · 2022Article
- Metal-Based Nanoparticles: Antibacterial Mechanisms and Biomedical Application.Microorganisms · 2022Review
- Unraveling the Antibiofilm Activity of a New Nanogold Resin for Dentures and Epithesis.Pharmaceutics · 2022Article
- A Review on Antibacterial Biomaterials in Biomedical Applications: From Materials Perspective to Bioinks Design.Polymers · 2022Review
- Antibiotic-free antimicrobial poly (methyl methacrylate) bone cements: A state-of-the-art review.World journal of orthopedics · 2022Review
- Translation of a spinal bone cement product from bench to bedside.Bioactive materials · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In total knee arthroplasty (TKA) and total hip replacement (THR) the restoration of the normal joint function represents a fundamental feature. A prosthetic joint must be able to provide motions and to transmit functional loads. As reported in the literature, the stress distribution may be altered in bones after the implantation of a total joint prosthesis. Some scientific works have also correlated uncemented TKA to a progressive decrease of bone density below the tibial component. Antibiotic-loaded bone cements are commonly employed in conjunction with systemic antibiotics to treat infections. Furthermore, nanoparticles with antimicrobial activity have been widely analysed. Accordingly, the current research was focused on a preliminary analysis of the mechanical and antibacterial activity of a PMMA-based bone cement loaded with gold nanoparticles. The obtained results demonstrated that nanocomposite cements with a specific concentration of gold nanoparticles improved the punching performance and antibacterial activity. However, critical aspects were found in the optimization of the nanocomposite bone cement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.