Evidence map›Paper›PMID 29744374›Full record

ArticleBio-protocol2018

Measurement of Intracellular ROS in

Dong Suk Yoon, Myon-Hee Lee, Dong Seok Cha

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 118 citations in OpenAlex.

  1. Article
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  10. Enhanced oxidative stress resilience inExperimental biology and medicine (Maywood, N.J.) · 2026
    Article
  11. Article
  12. Article
  13. Probiotic Modulation in Aging: Strain-Specific Geroprotective Effects inInternational journal of molecular sciences · 2025
    Article
  14. Article
  15. In Vivo Nanodiamond Quantum Sensing of Free Radicals in Caenorhabditis elegans Models.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  16. Article
  17. Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dong Suk YoonDepartment of Internal Medicine (Division of Hematology/Oncology), Brody School of Medicine at East Carolina University, Greenville, NC, United States.
Myon-Hee LeeDepartment of Internal Medicine (Division of Hematology/Oncology), Brody School of Medicine at East Carolina University, Greenville, NC, United States.
Dong Seok ChaDepartment of Oriental Pharmacy, College of Pharmacy, Woosuk University, Jeonbuk, Republic of Korea.
University of North Carolina at Chapel Hill · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Role of PUF-8/Pumilio in GLP-1/Notch-Mediated Germline Proliferation in C. elegansR15GM112174 · NIGMS · EAST CAROLINA UNIVERSITY · PI LEE, MYON HEE · 2015 to 2015
$367k
NIGMS NIH HHS R15 GM112174NIH HHS P40 OD010440
6 · The paper itself

Abstract

Reactive oxygen species (ROS) are generated during normal metabolic processes under aerobic conditions. Since ROS production initiates harmful radical chain reactions on cellular macromolecules, including lipid peroxidation, DNA mutation, and protein denaturation, it has been implicated in a wide spectrum of diseases such as cancer, cardiovascular disease, ischemia-reperfusion and aging. Over the past several decades, antioxidants have received explosive attention regarding their protective potential against these deleterious reactions. Accordingly, many analytical methodologies have been developed for the evaluation of the antioxidant capacity of compounds or complex biological samples. Herein, we introduce a simple and convenient method to detect

Indexed as

2′,7′-Dichlorofluorescein diacetateAntioxidantC. elegansReactive oxygen species

Identifiers

PMID29744374
PMCPMC5937271
OpenAlexW2794388470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.