ArticleClinical and experimental dental research2017
Putative periodontopathic bacteria and herpes viruses interactions in the subgingival plaque of patients with aggressive periodontitis and healthy controls.
Article in Clinical and experimental dental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Pooled it
- Differential Associations of Human Herpesviruses With Oral Bacteria and Periodontitis Severity: A Cross-Sectional Analysis.International dental journal · 2026Article
- Article
- Review
- Human Herpesviruses, Bacteria, and Fungi in Gingivitis and Periodontitis Pediatric Subjects: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- Exploring the Human Virome: Composition, Dynamics, and Implications for Health and Disease.Current microbiology · 2023Review
- Prevalence of Human Papillomavirus (HPV)-16 in Different Dental Infections in the Lebanese Population.Cureus · 2023Article
- Article
- The human oral virome: Shedding light on the dark matter.Periodontology 2000 · 2021Review
- Review
- The Loop-Mediated Isothermal Amplification Technique in Periodontal Diagnostics: A Systematic Review.Journal of clinical medicine · 2021Review
- Detection of Epstein-Barr Virus in Periodontitis: A Review of Methodological Approaches.Microorganisms · 2020Review
- Herpesvirus-bacteria synergistic interaction in periodontitis.Periodontology 2000 · 2020Review
- Is the progression rate of periodontitis related to subgingival biofilm composition or gingival crevicular fluid IL-1β and MMP-8 concentrations?Central-European journal of immunology · 2020Article
- Periodontal Status and Subgingival Biofilms in Cystic Fibrosis Adults.Polish journal of microbiology · 2019Article
- Microbiota and Its Role on Viral Evasion: Is It With Us or Against Us?Frontiers in cellular and infection microbiology · 2019Review
- Putative periodontopathic bacteria and herpes viruses interactions in the subgingival plaque of patients with aggressive periodontitis and healthy controls.Clinical and experimental dental research · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The microbial profile of aggressive periodontitis patients is considered to be complex with variations among populations in different geographical areas. The aim of this study was to assess the presences of 4 putative periodontopathic bacteria (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola) and 2 periodontal herpes viruses (Epstein-Barr virus type 1 [EBV-1] and human cytomegalovirus [HMCV]) in subgingival plaque of Sudanese subjects with aggressive periodontitis and healthy controls. The study group consisted of 34 subjects, 17 aggressive periodontitis patients and 17 periodontally healthy controls (14-19 years of age). Pooled subgingival plaque samples were collected and analyzed for detection of bacteria and viruses using loop-mediated isothermal amplification. Prevalence of subgingival A. actinomycetemcomitans, HCMV, and P. gingivalis were significantly higher among aggressive periodontitis patients than periodontally healthy controls. Coinfection with A. actinomycetemcomitans, HCMV, and/or EBV-1 was restricted to the cases. Increased risk of aggressive periodontitis was the highest when A. actinomycetemcomitans was detected together with EBV-1 (OD 49.0, 95% CI [2.5, 948.7], p = .01) and HCMV (OD 39.1, 95% CI [2.0, 754.6], p = .02). In Sudanese patients, A. actinomycetemcomitans and HCMV were the most associated test pathogens with aggressive periodontitis.
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Registered trials
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