Evidence map›Paper›PMID 29744180›Full record

ArticleClinical and experimental dental research2017

Effect of initial periodontal therapy on gingival crevicular fluid cytokine profile in subjects with chronic periodontitis.

A Zekeridou, C Giannopoulou, J Cancela, D Courvoisier, A Mombelli

Open access · goldAbstract read
In one paragraph

Article in Clinical and experimental dental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

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  10. Oral Dysbiosis and Inflammation in Parkinson's Disease.Journal of Parkinson's disease · 2021
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  15. HJournal of oral microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

A ZekeridouSchool of Dental Medicine, Division of Periodontology University of Geneva Rue Barthélemy-Menn 19 CH-1205 Geneva Switzerland.ORCID 0000-0001-9468-8958
C GiannopoulouSchool of Dental Medicine, Division of Periodontology University of Geneva Rue Barthélemy-Menn 19 CH-1205 Geneva Switzerland.
J CancelaSchool of Dental Medicine, Division of Periodontology University of Geneva Rue Barthélemy-Menn 19 CH-1205 Geneva Switzerland.
D CourvoisierDivision of Rheumatology University Hospitals of Geneva Geneva, Switzerland.
A MombelliSchool of Dental Medicine, Division of Periodontology University of Geneva Rue Barthélemy-Menn 19 CH-1205 Geneva Switzerland.
University of Geneva · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokines are thought to play an important role in the pathogenesis of periodontal disease. Because periodontal disease is known for its inhomogeneous distribution within the dentition, it is unclear to what extent the detection of various cytokines at different sites correlates with presence of disease. We evaluated whether levels of 12 cytokines in gingival crevicular fluid (GCF) discriminated periodontally diseased sites from healthy ones, or periodontally diseased persons from healthy ones, and assessed the impact of nonsurgical periodontal therapy on these readings. This study included 20 periodontally healthy persons (H) and 24 patients with chronic periodontitis (P). In every participant, we measured the plaque index, gingival index, probing pocket depth (PD), bleeding on probing, and recession at six sites of every tooth. GCF was collected with Durapore

Indexed as

cytokinesgingival crevice fluidperiodontal diseaseperiodontal treatment

Identifiers

PMID29744180
PMCPMC5719814
OpenAlexW2606529778

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.