Evidence map›Paper›PMID 29744136›Full record

ArticleClinical and experimental dental research2015

Inhibitors of bacterial protease enzymes for periodontal therapy.

Kalid N Hosn, Mary Margaret Jefferson, Carlton Leding, Solomon Shokouh-Amiri, Edwin L Thomas

Open access · goldAbstract read
In one paragraph

Article in Clinical and experimental dental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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  7. Inhibitors of bacterial protease enzymes for periodontal therapy.Clinical and experimental dental research · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kalid N HosnPeriodontology Department University of Tennessee Health Science Center Memphis Tennessee USA.
Mary Margaret JeffersonBioscience Research Department, College of Dentistry University of Tennessee Health Science Center Memphis Tennessee USA.
Carlton LedingBioscience Research Department, College of Dentistry University of Tennessee Health Science Center Memphis Tennessee USA.
Solomon Shokouh-AmiriBioscience Research Department, College of Dentistry University of Tennessee Health Science Center Memphis Tennessee USA.
Edwin L ThomasBioscience Research Department, College of Dentistry University of Tennessee Health Science Center Memphis Tennessee USA.
University of Tennessee Health Science Center · USBioscience Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Locally applied therapeutic agents have become established in the treatment of periodontal disease. Inhibition of human metalloproteases by metal-chelating antibiotics contributes to the utility of local therapy. Adding inhibitors of bacterial proteases might extend and improve local therapy. The periodontal pathogen

Indexed as

Microbial viabilityperiodontal diseasesPorphyromonas gingivalisprotease inhibitors

Identifiers

PMID29744136
PMCPMC5839262
OpenAlexW2214731927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.