ArticleFrontiers in endocrinology2018
Follicle Size on Day of Trigger Most Likely to Yield a Mature Oocyte.
Article in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03607409 (Role of Inhibin A as Biomarker for Ovarian Response to Stimulation With Gonadotropins for IVF Treatment), which is not on this map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of Inhibin A as Biomarker for Ovarian Response to Stimulation With Gonadotropins for IVF Treatment
Who cites it
34 citing papers in PubMed, 70 citations in OpenAlex.
- Germinal vesicle oocytes' rescue: a worthless treatment or a patient-centred approach? Eight years of clinical experience in poor prognosis patients.Human reproduction (Oxford, England) · 2026Article
- Empty Follicle Syndrome: Current Therapeutic Approaches and the Role of Triggering Agents in Assisted Reproductive Technology.Medical sciences (Basel, Switzerland) · 2026Review
- Effects of hCG-to-oocyte retrieval interval on oocyte performances in women with polycystic ovary syndrome undergoing progestin-primed ovarian stimulation: a retrospective cohort trial.Journal of assisted reproduction and genetics · 2026Article
- Medium-sized follicle proportion on the trigger day may be associated with higher live birth rate in fresh embryo transfer cycles among low-prognosis patients: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- The Trigger in IVF Cycles: Molecular Pathways and Clinical Implications.International journal of molecular sciences · 2025Review
- Predicting the optimal timing for triggering in controlled ovarian stimulation: mature oocytes retrieval predictor.Reproductive biology and endocrinology : RB&E · 2025Article
- Identification of Proteins and MicroRNAs with Prognostic Value for Assisted Reproduction Technology Outcomes in Follicular Fluid of Women with Endometriosis: A Pilot Study.International journal of molecular sciences · 2025Article
- Optimal leading follicle size for final oocyte maturation in POSEIDON group 3 and 4 poor responders undergoing assisted reproductive technology cycles.Journal of the Turkish German Gynecological Association · 2025Article
- A valuable predictive model for optimizing the timing of oocyte retrieval: a retrospective analysis of oocyte retrieval time in 49,961 oocyte pickup (OPU) cycles.Reproductive biology and endocrinology : RB&E · 2025Article
- Explainable artificial intelligence to identify follicles that optimize clinical outcomes during assisted conception.Nature communications · 2025Article
- Oocyte Competence, Embryological Outcomes and miRNA Signature of Different Sized Follicles from Poor Responder Patients.International journal of molecular sciences · 2024Article
- The prospect of artificial intelligence to personalize assisted reproductive technology.NPJ digital medicine · 2024Review
- Evaluating the heterogeneous effect of extended culture to blastocyst transfer on the implantation outcome via causal inference in fresh ICSI cycles.Journal of assisted reproduction and genetics · 2024Article
- Cai's prescription inhibits granulosa cell apoptosis through ARHGAP4 on poor ovarian responders.Journal of ovarian research · 2024Article
- From patient classification to optimized treatment in ART: the AMPLITUDE Delphi consensus.Frontiers in reproductive health · 2024Article
- The spectrum ofFrontiers in endocrinology · 2023Review
- Impact of follicular size categories on oocyte quality at trigger day in young and advanced-age patients undergoing GnRH-ant therapy.Frontiers in endocrinology · 2023Article
- Quantitative approaches in clinical reproductive endocrinology.Current opinion in endocrine and metabolic research · 2022Review
- High expression of CFTR in cumulus cells from mature oocytes is associated with high-quality of oocyte and subsequent embryonic development.Journal of assisted reproduction and genetics · 2022Article
- Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 3 countries.
Funding
Abstract
objectiveTo identify follicle sizes on the day of trigger most likely to yield a mature oocyte following hCG, GnRH agonist (GnRHa), or kisspeptin during IVF treatment.
designRetrospective analysis to determine the size of follicles on day of trigger contributing most to the number of mature oocytes retrieved using generalized linear regression and random forest models applied to data from IVF cycles (2014-2017) in which either hCG, GnRHa, or kisspeptin trigger was used.
settingHCG and GnRHa data were collected at My Duc Hospital, Ho Chi Minh City, Vietnam, and kisspeptin data were collected at Hammersmith Hospital, London, UK. PATIENTS: Four hundred and forty nine women aged 18-38 years with antral follicle counts 4-87 were triggered with hCG (
main outcome measureFollicle sizes on the day of trigger most likely to yield a mature oocyte.
resultsFollicles 12-19 mm on the day of trigger contributed the most to the number of oocytes and mature oocytes retrieved. Comparing the tertile of patients with the highest proportion of follicles on the day of trigger 12-19 mm, with the tertile of patients with the lowest proportion within this size range, revealed increases of 4.7 mature oocytes for hCG (
conclusionFollicles 12-19 mm on the morning of trigger administration were most likely to yield a mature oocyte following hCG, GnRHa, or kisspeptin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.