Evidence map›Paper›PMID 29743813›Full record

ArticleMediators of inflammation2018

Plasma Asprosin Concentrations Are Increased in Individuals with Glucose Dysregulation and Correlated with Insulin Resistance and First-Phase Insulin Secretion.

Yuren Wang, Hua Qu, Xin Xiong, Yuyang Qiu, Yong Liao, Yingchun Chen, Yi Zheng, Hongting Zheng

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05943158 (Effect of Myoinositol on Serum Asprosin Levels in Pregnant Women), which is not on this map. Cited by 84 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 3 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05943158 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Myoinositol on Serum Asprosin Levels in Pregnant Women

TypeinterventionalSponsorNear East University, TurkeyRan2021 to 2023Enrolled40ConditionsPregnancy RelatedArmsmyoinositol and folic acid, folic acid
3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 3 syntheses or guidelines pooled it, 180 citations in OpenAlex.

  1. Pooled it
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  17. Asprosin and Neuregulin 4 in Obesity in Children.Medicina (Kaunas, Lithuania) · 2025
    Article
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuren WangDepartment of Endocrinology, Translational Research Key Laboratory for Diabetes, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0002-3108-3799
Hua QuDepartment of Endocrinology, Translational Research Key Laboratory for Diabetes, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0002-4895-5979
Xin XiongDepartment of Endocrinology, Translational Research Key Laboratory for Diabetes, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0001-7773-4211
Yuyang QiuDepartment of Endocrinology, Translational Research Key Laboratory for Diabetes, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0002-2369-1719
Yong LiaoDepartment of Endocrinology, Armed Police Hospital of Chongqing, Chongqing, China.
Yingchun ChenDepartment of Medicinal Chemistry, College of Pharmacy, Third Military Medical University, Chongqing, China.ORCID 0000-0003-1902-0979
Yi ZhengDepartment of Endocrinology, Translational Research Key Laboratory for Diabetes, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0002-5945-4432
Hongting ZhengDepartment of Endocrinology, Translational Research Key Laboratory for Diabetes, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0002-6930-0103
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdipokines are reported to participate in many common pathologic processes of glucose dysregulation, such as insulin resistance,

objectiveTo detect the concentrations of plasma asprosin in subjects with impaired glucose regulation (IGR) and newly diagnosed type 2 diabetes (nT2DM) and its relationship to parameters of glucose and lipid metabolism, insulin resistance, and pancreatic

methods143 eligible participants were included and were divided into three groups including normal glucose regulation (NGR,

resultsPlasma asprosin levels were higher in IGR (82.40 ± 91.06 ng/mL,

conclusionsCirculating asprosin might be a predictor of early diagnosis in DM and might be a potential therapeutic target for prediabetes and T2DM.

Indexed as

AdipokinesBlood GlucoseFibrillin-1GlucoseGlucose Tolerance TestHumansInsulinInsulin ResistanceMicrofilament ProteinsPeptide FragmentsPeptide HormonesAdipokinesBlood GlucoseFBN1 protein, humanFibrillin-1GlucoseInsulinMicrofilament ProteinsPeptide FragmentsPeptide Hormones

Identifiers

PMID29743813
PMCPMC5883982
OpenAlexW2791782137

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.