Evidence map›Paper›PMID 29743794›Full record

ArticleJournal of clinical and experimental hepatology2018

Role of Indocyanine Green in Predicting Post-Transarterial Chemoembolization Liver Failure in Hepatocellular Carcinoma.

Shalimar, Sushil Jain, Shivanand R Gamanagatti, Saurabh Kedia, Bhaskar Thakur, Baibaswata Nayak, Harpreet Kaur, Deepak Gunjan, Shashi B Paul, Subrat K Acharya

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

ShalimarDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Sushil JainDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Shivanand R GamanagattiDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Saurabh KediaDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Bhaskar ThakurDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Baibaswata NayakDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Harpreet KaurDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Deepak GunjanDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Shashi B PaulDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Subrat K AcharyaDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPost-Transarterial Chemoembolization (TACE) Liver Failure (LF) is common in patients with Hepatocellular Carcinoma (HCC). No definitive objective parameters predict its occurrence. We assessed the role of Indocyanine Green (ICG) in prediction of post-TACE LF.

methodsConsecutive HCC patients with Child A/B class, categorized as Barcelona Clinic Liver Cancer (BCLC) staging A/B, were included between August 2012 and July 2014. All underwent ICG dynamics: Plasma Disappearance Rate (PDR) was recorded on the day of TACE. Area Under Receiver Operator Characteristic Curve (AUROC) of ICG-PDR was compared with existing prognostic scores: Model for End Stage Liver Disease (MELD), MELD-Na and Child-Turcotte-Pugh (CTP) using Hanley and McNeil method.

resultsA total of 43 patients, mean age (±sd) 55.1 ± 12.8 years were included; 35 (81.4%) patients were males. Post-TACE LF developed after 17 (28.8%) of 59 procedures. Patients with post-TACE LF had significantly elevated baseline bilirubin (

conclusionICG-PDR performs similar to MELD, MELD-Na and CTP score for predicting development of post-TACE LF.

Indexed as

ACLFAUROC, Area Under Receiver Operator Characteristic CurveBCLC, Barcelona Clinic Liver CancerHCC, Hepatocellular Carcinomahepatitis B virusICG, Indocyanine GreenLF, Liver FailureMELD, model For End Stage Liver DiseasePDR, Plasma Disappearance RateprognosisTACE, Trans-arterial Chemoembolizationtreatment

Identifiers

PMID29743794
PMCPMC5938326
OpenAlexW2621080365

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.