Evidence map›Paper›PMID 29743762›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2018

Thromboelastographic Analysis of Hemostatic Abnormalities in Dengue Patients Admitted in a Multidisciplinary Intensive Care Unit: A Cross-sectional Study.

V K Sureshkumar, Deepak Vijayan, Shamim Kunhu, Zuhail Mohamed, Sujith Thomas, Muraleedharan Raman

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Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Predictors of Clinically Significant Bleeding in Thrombocytopenic Dengue Patients Admitted to Intensive Care Unit: A Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  5. Article
  6. Article
  7. Thromboelastographic Analysis of Hemostatic Abnormalities in Dengue Patients Admitted in a Multidisciplinary Intensive Care Unit: A Cross-Sectional Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

V K SureshkumarDepartment of Critical Care Medicine, Kerala Institute of Medical Science, Trivandrum, Kerala, India.
Deepak VijayanDepartment of Critical Care Medicine, Kerala Institute of Medical Science, Trivandrum, Kerala, India.
Shamim KunhuDepartment of Critical Care Medicine, Kerala Institute of Medical Science, Trivandrum, Kerala, India.
Zuhail MohamedDepartment of Critical Care Medicine, SUT Hospital, Trivandrum, Kerala, India.
Sujith ThomasDepartment of Critical Care Medicine, Kerala Institute of Medical Science, Trivandrum, Kerala, India.
Muraleedharan RamanDepartment of Critical Care Medicine, Kerala Institute of Medical Science, Trivandrum, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDengue fever is an important tropical infection causing significant mortality. The pathophysiology of hematological abnormalities in dengue remains poorly studied. In this study, we analyzed the hematological abnormalities by thromboelastography (TEG).

methodsThis cross-sectional study evaluated complicated dengue patients with TEG. Thromboelastographic variables were categorized into six patterns: factor deficiency, platelet dysfunction, enzymatic hypercoagulability, combined enzymatic and platelet hypercoagulability, primary fibrinolysis, and secondary hyperfibrinolysis.

resultsTwenty-five patients were analyzed for coagulation abnormalities by TEG. Coagulation factor deficiency pattern was noted in 11 patients (44%) whereas 3 patients (12%) were found to have low fibrinogen level pattern. Low platelet function was noted in 4 (16%) patients. Enzymatic hypercoagulability and combined enzymatic and platelet hypercoagulability were noted in one patient each (4.5%). Secondary fibrinolysis was noted in 1 patient (5%) and primary fibrinolysis in 3 (15.8%) patients. Factor deficiency pattern and low fibrinogen pattern were not significantly associated with hepatitis (

conclusionFactor deficiency pattern was the major abnormality noted in dengue patients followed by platelet dysfunction and primary fibrinolysis. Platelet count did not show significant association with platelet function. aPTT did not show significant association with factor deficiency and low fibrinogen patterns. Factor deficiency pattern and low fibrinogen pattern did not show significant association with hepatitis.

Indexed as

Denguehematological abnormalitythromboelastography

Identifiers

PMID29743762
PMCPMC5930527

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.